BNP Protein

Catalog No. ABIN987787

Product Details

Target: BNP (Brain Natriuretic Peptide (BNP))

Origin: Human

Source: Escherichia coli (E. coli)

Sequence: SPKMVQGSGC FGRKMDRISS SSGLGCKVLR R

Purity: > 97 % by SDS-PAGE and HPLC analyses.

Endotoxin Level: Level Less than 1EU/µg of rHuBNP as determined by LAL method

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20°C. Further dilutions should be made in appropriate buffered solutions.

Storage: 4 °C

References

Moltzau, Aronsen, Meier, Skogestad, Ørstavik, Lothe, Sjaastad, Skomedal, Osnes, Levy, Qvigstad: "Different compartmentation of responses to brain natriuretic peptide and C-type natriuretic peptide in failing rat ventricle." in: The Journal of pharmacology and experimental therapeutics, Vol. 350, Issue 3, pp. 681-90, (2014) (PubMed).

Lu, Fu, Chen, Lu, Yao, Shen, Gu: "Multiplex detection of B-type natriuretic peptide, cardiac troponin I and C-reactive protein with photonic suspension array." in: PLoS ONE, Vol. 7, Issue 7, pp. e41448, (2012) (PubMed).

Target Details

Target: BNP (Brain Natriuretic Peptide (BNP))

Abstract: BNP Products

Synonyms: bnp Protein, BNP1 Protein, NPPB Protein, BNP Protein, Bnf Protein, AA408272 Protein, B-type natriuretic peptide Protein, natriuretic peptide B Protein, natriuretic peptide type B Protein, nppb Protein, NPPB Protein, Nppb Protein

Background: Natriuretic Peptide Precursor B acts as a cardiac hormone with a variety of biological actions including natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. It is thought to play a key role in cardiovascular homeostasis. Helps restore the body's salt and water balance. Improves heart function. Synonym:. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

Molecular Weight: 3464 Da, a single non-glycosylated polypeptide chain containing 32 amino acids.

Pathways: Hormone Activity