Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
functional NHE2, but not NHE1 (show SLC9A1 ELISA Kits), is essential for mouse gastric epithelial restitution and TFFs activate epithelial repair via NHE2
thick ascending cells retain structural and functional properties of their in vivo thick ascending counterparts and express functional NHE2 protein in the apical membrane, which may be inhibited by nitric oxide
High NHE2 expression in crypts. Role for NHE2 in cryptal pH(i) and volume homeostasis.
Bicarbonate reabsorption in the distal tubule of mice with genetic knockouts at NHE2 or NHE3 (show SLC9A3 ELISA Kits).
This study demonstrated that constitutive absence of NHE2 results in a compensatory increase in a Na(+)-dependent, EIPA-sensitive acid extruder distinct from NHE1 (show SLC9A1 ELISA Kits), NHE3 (show SLC9A3 ELISA Kits), or SITS-sensitive transporters.
Here, we show that NHE10 (show NHEDC2 ELISA Kits) is highly expressed in OCs in response to receptor activator of nuclear factor-kappaB ligand signaling and is required for OC differentiation and survival.
Renal tissue renin (show REN ELISA Kits) activity and plasma renin (show REN ELISA Kits) concentration were elevated three- and twofold, respectively, in NHE2 knckout mice.
Mucosa from NHE2(-/-) mice displayed a shift of occludin (show OCLN ELISA Kits) and claudin-1 (show CLDN1 ELISA Kits) expression to the Triton-X-soluble membrane fractions and showed disruption of occludin (show OCLN ELISA Kits) and claudin-1 (show CLDN1 ELISA Kits) localization patterns following injury.
These data indicate that the acid-dependent NHE2 stimulation is implemented by transcriptional upregulation of NHE2 via acid-induced Egr-1 (show EGR1 ELISA Kits) in the intestinal epithelial cells.
Phosphorylation of nPKC-delta results in activation of ERK1/2 kinase and subsequent induction of Egr-1. Subsequently, Egr-1 directly targets NHE2 promoter and promotes NHE2 transcriptional upregulation by interaction with NHE2-PMA response element.
In humans, NHE2 transcripts appear to be gestationally regulated, which may contribute to changes in NHE activity.
expression of the human NHE2 promoter is controlled by Sp1 (show PSG1 ELISA Kits) and Sp3 (show SP3 ELISA Kits) by interactions with the proximal promoter and the transcription initiation site of NHE2
No mutation was found in the coding regions and intron-exon boundaries of the genes for CA II (show CA2 ELISA Kits), CA IV (show CA4 ELISA Kits), CA XIV (show CA14 ELISA Kits), kNCB1, NHE3 (show SLC9A3 ELISA Kits), NHE8 (show SLC9A8 ELISA Kits), NHRF1, NHRF2 and SLC26A6 (show SLC26A6 ELISA Kits) amplified from genomic DNA of family members with pRTA.
T84 human colon cells contain three isoforms of the Na+/H+ exchanger, NHE1 (show SLC9A1 ELISA Kits), NHE2, and NHE4 (show SLC9A4 ELISA Kits), but not the Cl-dependent NHE
Functional coupling of the downregulated in adenoma Cl-/base exchanger DRA (show SLC26A3 ELISA Kits) and the apical Na+/H+ exchangers NHE2 and NHE3 (show SLC9A3 ELISA Kits) in intestinal epithelial cells.
Report morphological adaptation with preserved proliferation/NHE2 content in the colon of patients with short bowel syndrome.
The functional and molecular expression of NHEs in cultured human endolymphatic sac (show ADCY10 ELISA Kits) (ES) epithelial cells was determined and the effect of IFN-gamma (show IFNG ELISA Kits) on NHE function, was examined.
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Seems to play an important role in colonic sodium absorption.
sodium/hydrogen exchanger 2 (nhe2)
, solute carrier family 9 (sodium/hydrogen exchanger), member 2
, solute carrier family 9 sodium/hydrogen exchanger member 2
, sodium/hydrogen exchanger 2
, Na(+)/H(+) exchanger 2
, solute carrier family 9 (sodium/hydrogen exchanger)
, solute carrier family 9 member 2
, Na/H ion exchanger
, Solute carrier family 9 (sodium/hydrogen exchanger 2), antiporter 2, Na+/H+ (Na+/H+ exchanger 2)
, solute carrier family 9, member 2