Browse our Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) ELISA Kits

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Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 ELISA Kits (SLC9A3R1)
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Synonyms:
EBP-50, EBP50, NHE-RF, NHERF, NHERF-1, NHERF1, NPHLOP2, SLC9A3R1
list all ELISA KIts Gene Name GeneID UniProt
Human SLC9A3R1 SLC9A3R1 9368 O14745
Mouse SLC9A3R1 SLC9A3R1 26941 P70441
Rat SLC9A3R1 SLC9A3R1 59114 Q9JJ19

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More ELISA Kits for Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 Interaction Partners

Human Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) interaction partners

  1. NHERF1/EBP50 encompasses the regulation of several major signaling pathways engaged in cancer, including the receptor tyrosine kinases PDGFR (show PDGFRB ELISA Kits) and EGFR (show EGFR ELISA Kits), PI3K (show PIK3CA ELISA Kits)/PTEN/AKT (show AKT1 ELISA Kits) and Wnt (show WNT2 ELISA Kits)-beta-catenin (show CTNNB1 ELISA Kits) pathways.

  2. Data demonstrated that EBP50 overexpression inhibited the adhesion and migration of breast and cervical cancer cell lines and suppressed MMP-2 (show MMP2 ELISA Kits) activity in these cells; while its knockdown promoted cell adhesion and migration, and enhanced the activity of MMP-2 (show MMP2 ELISA Kits).This study reveals the anti-metastatic effect and a new mechanism of EBP50 action in breast and cervical cancer cells.

  3. Data provide evidence for an important role of NHERF1 in the epithelial-mesenchymal transition of non-small-cell lung cancer cells, as well as migration.

  4. This interaction is promoted by EPAC1 (show RAPGEF3 ELISA Kits) activation, triggering its translocation to the plasma membrane and binding to NHERF1. Our findings identify a new CFTR (show CFTR ELISA Kits)-interacting protein and demonstrate that cAMP activates CFTR (show CFTR ELISA Kits) through two different but complementary pathways - the well-known PKA-dependent channel gating pathway and a new mechanism regulating endocytosis that involves EPAC1 (show RAPGEF3 ELISA Kits).

  5. we show here that NHERF1 loss from the PM is oncogenic in vivo through its influence on Wnt (show WNT2 ELISA Kits)-APC (show APC ELISA Kits)-beta-catenin (show CTNNB1 ELISA Kits) and Hippo-YAP (show YAP1 ELISA Kits) pathways.

  6. High EBP50 expression is associated with cervical cancer.

  7. Using neutron spin echo spectroscopy (NSE (show ENO2 ELISA Kits)), the authors show salt-concentration-dependent excitation of nanoscale motion at the tip of the C-terminal tail in the phosphomimic S339D/S340D mutant.

  8. data highlight sequences in PTHR (show PTHLH ELISA Kits) that contribute to NHERF1 interaction and can be altered to prevent phosphorylation-mediated inhibition

  9. NHERF1 acts with PMCA2 (show ATP2B2 ELISA Kits) to regulate HER2 (show ERBB2 ELISA Kits) signaling and membrane retention in breast cancers

  10. COOH-terminal sequences mediate enhanced NHERF1 interaction and facilitate the localization of CFTR (show CFTR ELISA Kits).

Pig (Porcine) Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) interaction partners

  1. Along with several single loci, the epistatic QTLs, SLC9A3R1 and NOS2 control for total number of piglets born and number of piglets born alive in a F(2) Iberian by Meishan intercross.

Mouse (Murine) Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) interaction partners

  1. The results provide evidence that NHERF1 (show SLC9A3R2 ELISA Kits) mediates K(+) current activity through acceleration of the surface expression of ROMK1 (show KCNJ1 ELISA Kits) K(+) channels in M-1 cells.

  2. The NHERF1 (show SLC9A3R2 ELISA Kits) is as putative molecular organizer of signal transduction in vomeronasal neurons.

  3. we show here that NHERF1 (show SLC9A3R2 ELISA Kits) loss from the PM is oncogenic in vivo through its influence on Wnt (show WNT2 ELISA Kits)-APC (show APC ELISA Kits)-beta-catenin (show CTNNB1 ELISA Kits) and Hippo-YAP (show YAP1 ELISA Kits) pathways.

  4. NHERF1 (show SLC9A3R2 ELISA Kits) mediates ANG II (show AGT ELISA Kits)-induced activation of renal NHE3 (show SLC9A3 ELISA Kits), which requires coordination between IRBIT (show AHCYL1 ELISA Kits) and the NHERF1 (show SLC9A3R2 ELISA Kits) PDZ1 domain in binding and transporting NHE3 (show SLC9A3 ELISA Kits)

  5. These results indicate that PTH (show PTH ELISA Kits)-mediated inhibition of renal phosphate transport involves phosphorylation of S77 of the NHERF-1 PDZ (show INADL ELISA Kits) I domain and the dissociation of NHERF-1/Npt2a (show SLC34A1 ELISA Kits) complexes.

  6. Results strongly support an important role for NHERF1 (show SLC9A3R2 ELISA Kits) in the regulation of Planar Cell Polarity signaling and the development of functional motile cilia.

  7. the activation of PTEN and NHERF-1 may impede the evolution of macrophages beyond the M1 into M2 phenotype in tumor microenvironment.

  8. Data show that interaction of the inducible nitric oxide synthase (iNOS (show NOS2 ELISA Kits)) C-terminus with the PDZ (show INADL ELISA Kits) domains of EBP50 protein or Pdzk1 (show PDZK1 ELISA Kits) protein CAP70 (show PDZK1 ELISA Kits) resulted greater nitric oxide (NO) synthesis.

  9. The expression of EBP50 was not significantly different in the pseudopregnant uterus and decreased in the uteri subjected to activation of delayed implantation.

  10. NHERF1 (show SLC9A3R2 ELISA Kits) is differentially distributed to rafts and non-raft brush border membrane fractions of NHE3 (show SLC9A3 ELISA Kits).

Cow (Bovine) Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) interaction partners

  1. study found mainly nuclear localization of EBP50 in interphase cells, and its redistribution to cytoplasm during mitosis parallel with its phosphorylation; PP2A was identified as an interacting protein of EBP50 during pro-, prometa-, meta-, ana (show BTG3 ELISA Kits)-, telophase, and early cytokinesis

Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) Antigen Profile

Antigen Summary

This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.

Alternative names and synonyms associated with Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1)

  • solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 (SLC9A3R1) Elisa Kit
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 (SLC9A3R1) Elisa Kit
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 (Slc9a3r1) Elisa Kit
  • solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 (Slc9a3r1) Elisa Kit
  • EBP-50 Elisa Kit
  • EBP50 Elisa Kit
  • NHE-RF Elisa Kit
  • NHERF Elisa Kit
  • NHERF-1 Elisa Kit
  • NHERF1 Elisa Kit
  • NPHLOP2 Elisa Kit
  • SLC9A3R1 Elisa Kit

Protein level used designations for SLC9A3R1

Na(+)/H(+) exchange regulatory cofactor NHE-RF1 , Na+/H+ exchange regulatory co-factor , ezrin-radixin-moesin binding phosphoprotein-50 , ezrin-radixin-moesin-binding phosphoprotein 50 , regulatory cofactor of Na(+)/H(+) exchanger , solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1 , solute carrier family 9 isoform A3 regulatory factor 1 , EBP50 , NHERF-1 , sodium-hydrogen exchanger regulatory factor 1 , solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 , solute carrier family 9 sodium/hydrogen exchanger member 3 regulator 1 , solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1 , ERM-binding phosphoprotein , Na(+)/H(+) exchange regulatory cofactor NHE-RF , solute carrier family 9 isoform 3 regulatory factor 1

GENE ID SPECIES
9368 Homo sapiens
422108 Gallus gallus
454865 Pan troglodytes
483299 Canis lupus familiaris
703933 Macaca mulatta
780527 Ovis aries
100009196 Oryctolagus cuniculus
100233201 Sus scrofa
26941 Mus musculus
59114 Rattus norvegicus
505242 Bos taurus
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