EFNB2A antibody (AA 163-194)

Catalog No. ABIN1881282

Product Details anti-EFNB2A Antibody

Target: EFNB2A

Binding Specificity: AA 163-194

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EFNB2A antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DANRE efnb2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-194 amino acids from the Central region of DANRE efnb2a.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-EFNB2A antibody (ABIN1881282)

Chan, Mably, Serluca, Chen, Goldstein, Thomas, Cleary, Brennan, Fishman, Roberts: "Morphogenesis of prechordal plate and notochord requires intact Eph/ephrin B signaling." in: Developmental biology, Vol. 234, Issue 2, pp. 470-82, (2001) (PubMed).

Durbin, Brennan, Shiomi, Cooke, Barrios, Shanmugalingam, Guthrie, Lindberg, Holder: "Eph signaling is required for segmentation and differentiation of the somites." in: Genes & development, Vol. 12, Issue 19, pp. 3096-109, (1998) (PubMed).

Target Details for EFNB2A

Target: EFNB2A

Abstract: EFNB2A Products

Background: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with ephb4 may play a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration (By similarity).

Molecular Weight: 36724

NCBI Accession: NP_571098

UniProt: O73874