MYL4 antibody (N-Term)

Catalog No. ABIN1881562

Product Details anti-MYL4 Antibody

Target: MYL4 (Myosin Light Chain 4, Alkali, Atrial, Embryonic (MYL4))

Binding Specificity: AA 1-30, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYL4 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MYL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MYL4.

Clone: RB40527

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-MYL4 antibody (ABIN1881562)

Haase, Dobbernack, Tünnemann, Karczewski, Cardoso, Petzhold, Schlegel, Lutter, Pierschalek, Behlke, Morano: "Minigenes encoding N-terminal domains of human cardiac myosin light chain-1 improve heart function of transgenic rats." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 20, Issue 7, pp. 865-73, (2006) (PubMed).

Arrell, Neverova, Fraser, Marbán, Van Eyk: "Proteomic analysis of pharmacologically preconditioned cardiomyocytes reveals novel phosphorylation of myosin light chain 1." in: Circulation research, Vol. 89, Issue 6, pp. 480-7, (2001) (PubMed).

Target Details for MYL4

Target: MYL4 (Myosin Light Chain 4, Alkali, Atrial, Embryonic (MYL4))

Alternative Name: MYL4 (MYL4 Products)

Synonyms: ALC1 antibody, AMLC antibody, GT1 antibody, ELC antibody, ELC1a antibody, MLC1a antibody, Myla antibody, myosin, light chain 4 antibody, myosin light chain 4 antibody, myosin, light polypeptide 4 antibody, Myl4 antibody, MYL4 antibody

Background: Myosin is a hexameric ATPase cellular motor protein. It is composed of two myosin heavy chains, two nonphosphorylatable myosin alkali light chains, and two phosphorylatable myosin regulatory light chains. This gene encodes a myosin alkali light chain that is found in embryonic muscle and adult atria. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Molecular Weight: 21565

NCBI Accession: NP_001002841, NP_002467

UniProt: P12829

Pathways: Myometrial Relaxation and Contraction