HEY2 antibody (C-Term)

Catalog No. ABIN1881411

Product Details anti-HEY2 Antibody

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Binding Specificity: AA 295-322, C-Term

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEY2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DANRE hey2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-322 amino acids from the C-terminal region of DANRE hey2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-HEY2 antibody (ABIN1881411)

Winkler, Elmasri, Klamt, Volff, Gessler: "Characterization of hey bHLH genes in teleost fish." in: Development genes and evolution, Vol. 213, Issue 11, pp. 541-53, (2003) (PubMed).

Zhong, Childs, Leu, Fishman: "Gridlock signalling pathway fashions the first embryonic artery." in: Nature, Vol. 414, Issue 6860, pp. 216-20, (2001) (PubMed).

Zhong, Rosenberg, Mohideen, Weinstein, Fishman: "gridlock, an HLH gene required for assembly of the aorta in zebrafish." in: Science (New York, N.Y.), Vol. 287, Issue 5459, pp. 1820-4, (2000) (PubMed).

Target Details for HEY2

Target: HEY2 (Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Alternative Name: hey2 (HEY2 Products)

Synonyms: CHF1 antibody, GRIDLOCK antibody, GRL antibody, HERP1 antibody, HESR2 antibody, HRT2 antibody, bHLHb32 antibody, Herp1 antibody, Hrt2 antibody, hesr2 antibody, grl antibody, zgc:136746 antibody, hes related family bHLH transcription factor with YRPW motif 2 antibody, hairy/enhancer-of-split related with YRPW motif 2 antibody, hes-related family bHLH transcription factor with YRPW motif 2 antibody, HEY2 antibody, Hey2 antibody, hey2 antibody

Background: Transcriptional repressor (By similarity). Downstream effector of Notch signaling which regulates cell fate choice in angioblasts. Represses the venous cell fate, thereby promoting the arterial cell fate and aorta formation.

Molecular Weight: 34329

NCBI Accession: NP_571697

UniProt: Q9I9L0

Pathways: Regulation of Muscle Cell Differentiation