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NEK6 antibody (N-Term)

NEK6 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB2965 unconjugated
Catalog No. ABIN1882104
  • Target See all NEK6 Antibodies
    NEK6 (NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6))
    Binding Specificity
    • 15
    • 8
    • 8
    • 6
    • 3
    • 3
    • 1
    • 1
    AA 8-39, N-Term
    Reactivity
    • 35
    • 25
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 46
    • 4
    Rabbit
    Clonality
    • 44
    • 6
    Polyclonal
    Conjugate
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEK6 antibody is un-conjugated
    Application
    • 22
    • 20
    • 16
    • 13
    • 13
    • 9
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This NEK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-39 amino acids from the N-terminal region of human NEK6.
    Clone
    RB2965
    Isotype
    Ig Fraction
    Top Product
    Discover our top product NEK6 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Takeno, Takemasa, Doki, Yamasaki, Miyata, Takiguchi, Fujiwara, Matsubara, Monden: "Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis." in: British journal of cancer, Vol. 99, Issue 8, pp. 1307-15, (2008) (PubMed).

    Belham, Roig, Caldwell, Aoyama, Kemp, Comb, Avruch: "A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases." in: The Journal of biological chemistry, Vol. 278, Issue 37, pp. 34897-909, (2003) (PubMed).

    Lizcano, Deak, Morrice, Kieloch, Hastie, Dong, Schutkowski, Reimer, Alessi et al.: "Molecular basis for the substrate specificity of NIMA-related kinase-6 (NEK6). Evidence that NEK6 does not phosphorylate the hydrophobic motif of ribosomal S6 protein kinase and serum- and ..." in: The Journal of biological chemistry, Vol. 277, Issue 31, pp. 27839-49, (2002) (PubMed).

    Hashimoto, Akita, Hibino, Kohri, Nakanishi: "Identification and characterization of Nek6 protein kinase, a potential human homolog of NIMA histone H3 kinase." in: Biochemical and biophysical research communications, Vol. 293, Issue 2, pp. 753-8, (2002) (PubMed).

  • Target
    NEK6 (NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6))
    Alternative Name
    NEK6 (NEK6 Products)
    Synonyms
    1300007C09Rik antibody, si:ch211-167p9.4 antibody, ATNEK5 antibody, MOE17.17 antibody, NIMA-RELATED KINASE5 antibody, NIMA-related kinase 5 antibody, SID6-1512 antibody, NIMA (never in mitosis gene a)-related expressed kinase 6 antibody, NIMA-related kinase 6 antibody, NIMA related kinase 6 antibody, Serine/Threonine kinase catalytic domain protein antibody, NIMA-related kinase 6 S homeolog antibody, Nek6 antibody, nek6 antibody, NEK6 antibody, NEK5 antibody, nek6.S antibody
    Background
    NEK6 is a serine/threonine kinase that controls initiation of mitosis. NEK6 is activated during M phase. It is required for chromosome segregation at metaphase-anaphase transition and therefore for mitotic progression. Inhibition of activity results in apoptosis.
    Molecular Weight
    35714
    NCBI Accession
    NP_001138473, NP_001159639, NP_001159640, NP_001159641, NP_001159642, NP_001159643, NP_055212
    UniProt
    Q9HC98
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