SGK3 antibody (AA 108-139)

Catalog No. ABIN1882132

Product Details anti-SGK3 Antibody

Target: SGK3 (serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3))

Binding Specificity: AA 108-139

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGK3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This SGK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-139 amino acids from the Central region of human SGK3.

Clone: RB1190

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-SGK3 antibody (ABIN1882132)

Meng, Yamagiwa, Taffetani, Han, Patel: "IL-6 activates serum and glucocorticoid kinase via p38alpha mitogen-activated protein kinase pathway." in: American journal of physiology. Cell physiology, Vol. 289, Issue 4, pp. C971-81, (2005) (PubMed).

Friedrich, Feng, Cohen, Risler, Vandewalle, Bröer, Wang, Pearce, Lang: "The serine/threonine kinases SGK2 and SGK3 are potent stimulators of the epithelial Na+ channel alpha,beta,gamma-ENaC." in: Pflügers Archiv : European journal of physiology, Vol. 445, Issue 6, pp. 693-6, (2003) (PubMed).

Embark, Böhmer, Vallon, Luft, Lang: "Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms." in: Pflügers Archiv : European journal of physiology, Vol. 445, Issue 5, pp. 601-6, (2003) (PubMed).

Brickley, Mikosz, Hagan, Conzen: "Ubiquitin modification of serum and glucocorticoid-induced protein kinase-1 (SGK-1)." in: The Journal of biological chemistry, Vol. 277, Issue 45, pp. 43064-70, (2002) (PubMed).

Dai, Yu, He, Chen, Yu, Yang, Xu, Ling, Zhao: "Human serum and glucocorticoid-inducible kinase-like kinase (SGKL) phosphorylates glycogen syntheses kinase 3 beta (GSK-3beta) at serine-9 through direct interaction." in: Biochemical and biophysical research communications, Vol. 293, Issue 4, pp. 1191-6, (2002) (PubMed).

Gamper, Fillon, Feng, Friedrich, Lang, Henke, Huber, Kobayashi, Cohen, Lang: "K+ channel activation by all three isoforms of serum- and glucocorticoid-dependent protein kinase SGK." in: Pflügers Archiv : European journal of physiology, Vol. 445, Issue 1, pp. 60-6, (2002) (PubMed).

Target Details for SGK3

Target: SGK3 (serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3))

Alternative Name: SGK3 (SGK3 Products)

Synonyms: CISK antibody, SGK2 antibody, SGKL antibody, 2510015P22Rik antibody, A330005P07Rik antibody, Cisk antibody, fy antibody, fz antibody, Sgkl antibody, zgc:162253 antibody, serum/glucocorticoid regulated kinase family member 3 antibody, serum/glucocorticoid regulated kinase 3 antibody, serum/glucocorticoid regulated kinase family, member 3 antibody, serine/threonine-protein kinase Sgk3 antibody, SGK3 antibody, Sgk3 antibody, LOC464217 antibody, sgk3 antibody, LOC100231693 antibody, LOC100343709 antibody, LOC100052030 antibody, LOC100521447 antibody

Background: SGK3, a Ser/Thr protein kinase, is similar to serum- and glucocorticoid-induced protein kinase (SGK), but this gene product is not induced by serum or glucocorticoids. Expression is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK.

Molecular Weight: 57108

NCBI Accession: NP_001028750, NP_001191102, NP_037389, NP_733827

UniProt: Q96BR1