SYNE2 antibody (AA 1-459)

Catalog No. ABIN1042628

Product Details anti-SYNE2 Antibody

Target: SYNE2 (Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2))

Binding Specificity: AA 1-459

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SYNE2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Electron Microscopy (EM)

Purification: Protein G purified

Immunogen: Residues 1-459 of human Nesprin-2

Clone: K20-478-5

Application Details

Application Notes: Optimal antibody dilution should be determined by titration, however as guideline try at 1:2500 for western blot, & 1:500 for IF

Comment:

Myeloma, fusion partners: Pai / BalbC

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified antibody in PBS + 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-SYNE2 antibody (ABIN1042628)

Neumann, Schneider, Daugherty, Gottardi, Eming, Beijer, Noegel, Karakesisoglou: "Nesprin-2 interacts with {alpha}-catenin and regulates Wnt signaling at the nuclear envelope." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34932-8, (2010) (PubMed).

Libotte, Zaim, Abraham, Padmakumar, Schneider, Lu, Munck, Hutchison, Wehnert, Fahrenkrog, Sauder, Aebi, Noegel, Karakesisoglou: "Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope." in: Molecular biology of the cell, Vol. 16, Issue 7, pp. 3411-24, (2005) (PubMed).

Zhen, Libotte, Munck, Noegel, Korenbaum: "NUANCE, a giant protein connecting the nucleus and actin cytoskeleton." in: Journal of cell science, Vol. 115, Issue Pt 15, pp. 3207-22, (2002) (PubMed).

Target Details for SYNE2

Target: SYNE2 (Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2))

Alternative Name: Nesprin 2 (SYNE2 Products)

Synonyms: EDMD5 antibody, NUA antibody, NUANCE antibody, Nesp2 antibody, Nesprin-2 antibody, SYNE-2 antibody, TROPH antibody, SYNE2 antibody, nua antibody, edmd5 antibody, nuance antibody, syne-2 antibody, nesprin-2 antibody, 6820443O06Rik antibody, AW546258 antibody, D12Ertd777e antibody, Nesp2g antibody, mKIAA1011 antibody, RGD1305248 antibody, spectrin repeat containing nuclear envelope protein 2 antibody, spectrin repeat containing, nuclear envelope 2 antibody, SYNE2 antibody, syne2 antibody, Syne2 antibody

Background: Synonyms:
DKFZP434H2235 antibody,DKFZp686E01115 antibody,DKFZp686H1931 antibody,FLJ11014 antibody,FLJ43727 antibody,FLJ45710 antibody,FLJ46790 antibody,KIAA1011 antibody,Nesprin2 antibody,NUA antibody,NUANCE antibody,Nuclear envelope spectrin repeat protein 2 antibody,Nucleus and actin connecting element antibody,Nucleus and actin connecting element protein antibody,Protein NUANCE antibody,Spectrin repeat containing nuclear envelope 2 antibody,Synaptic nuclear envelope protein 2 antibody,Synaptic nuclei expressed gene 2 antibody,SYNE 2 antibody,SYNE2 antibody

Gene ID: 19052

OMIM: 608442

Pathways: Maintenance of Protein Location