Keratin 72 antibody (AA 313-342)

Catalog No. ABIN1881487

Product Details anti-Keratin 72 Antibody

Target: Keratin 72 (KRT72)

Binding Specificity: AA 313-342

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Keratin 72 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This KRT72 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-342 amino acids from the Central region of human KRT72.

Clone: RB40960

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-Keratin 72 antibody (ABIN1881487)

Langbein, Rogers, Praetzel, Winter, Schweizer: "K6irs1, K6irs2, K6irs3, and K6irs4 represent the inner-root-sheath-specific type II epithelial keratins of the human hair follicle." in: The Journal of investigative dermatology, Vol. 120, Issue 4, pp. 512-22, (2003) (PubMed).

Porter, Corden, Lunny, Smith, Lane, McLean: "Keratin K6irs is specific to the inner root sheath of hair follicles in mice and humans." in: The British journal of dermatology, Vol. 145, Issue 4, pp. 558-68, (2001) (PubMed).

Target Details for Keratin 72

Target: Keratin 72 (KRT72)

Alternative Name: KRT72 (KRT72 Products)

Synonyms: K6IRS2 antibody, K6irs antibody, KRT6 antibody, KRT6IRS2 antibody, AI507495 antibody, K6irs2 antibody, Krt2-35 antibody, Krt72-ps antibody, Kb35 antibody, KRT72 antibody, keratin 72 antibody, keratin, type II cytoskeletal 72 antibody, KRT72 antibody, Krt72 antibody, LOC100347394 antibody

Background: Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 55877

NCBI Accession: NP_001139697, NP_001139698, NP_542785

UniProt: Q14CN4