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CD28 antibody

CD28 Reactivity: Human FACS, Func, IHC Host: Mouse Monoclonal B-T3 unconjugated
Catalog No. ABIN1383845
  • Target See all CD28 Antibodies
    CD28
    Reactivity
    • 172
    • 128
    • 58
    • 38
    • 21
    • 20
    • 12
    • 12
    • 7
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 125
    • 79
    • 33
    • 16
    • 8
    • 3
    • 2
    • 1
    Mouse
    Clonality
    • 187
    • 74
    • 3
    Monoclonal
    Conjugate
    • 87
    • 30
    • 29
    • 21
    • 14
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD28 antibody is un-conjugated
    Application
    • 198
    • 94
    • 47
    • 47
    • 38
    • 30
    • 26
    • 26
    • 19
    • 17
    • 13
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Functional Studies (Func), Immunohistochemistry (IHC)
    Specificity
    Recognises the B7/BB1 receptor (B7/BB1 R), a 44 kDa protein
    Purification
    Ion exchange chromatography
    Sterility
    0.22 μm filtered
    Immunogen
    U266 cell line,Myeloma X63/AG.8653 x Balb/c spleen cells
    Clone
    B-T3
    Isotype
    IgG2a, kappa
    Biological Activity Comment
    Inhibits mixed lymphocyte culture. Co-stimulates T-cell proliferation
    Top Product
    Discover our top product CD28 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
    Preservative
    Without preservative
    Storage
    4 °C
    Storage Comment
    Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
  • Vermot-Desroches, Sergent, Bonnin, Wijdenes: "Characterization of monoclonal antibodies directed against trail or trail receptors." in: Cellular immunology, Vol. 236, Issue 1-2, pp. 86-91, (2005) (PubMed).

    Roth, Yssel, Pene, Chavez, Schertzer, Lansdorp, Spits, Luiten: "Telomerase levels control the lifespan of human T lymphocytes." in: Blood, Vol. 102, Issue 3, pp. 849-57, (2003) (PubMed).

    Luiten, Péne, Yssel, Spits: "Ectopic hTERT expression extends the life span of human CD4+ helper and regulatory T-cell clones and confers resistance to oxidative stress-induced apoptosis." in: Blood, Vol. 101, Issue 11, pp. 4512-9, (2003) (PubMed).

    Sauce, Bodinier, Garin, Petracca, Tonnelier, Duperrier, Melo, Apperley, Ferrand, Hervé, Lang, Tiberghien, Robinet: "Retrovirus-mediated gene transfer in primary T lymphocytes impairs their anti-Epstein-Barr virus potential through both culture-dependent and selection process-dependent mechanisms." in: Blood, Vol. 99, Issue 4, pp. 1165-73, (2002) (PubMed).

    Jourdan, Abbal, Noraz, Hori, Uchiyama, Vendrell, Bousquet, Taylor, Pène, Yssel, Nora: "IL-4 induces functional cell-surface expression of CXCR4 on human T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 9, pp. 4153-7, (1998) (PubMed).

  • Target
    CD28
    Alternative Name
    CD28 (CD28 Products)
    Synonyms
    Tp44 antibody, CD28RNA antibody, cd28 antibody, CD28 molecule antibody, CD28 antigen antibody, Cd28 molecule antibody, CD28 molecule L homeolog antibody, CD28 antibody, Cd28 antibody, cd28.L antibody
    Molecular Weight
    44 kDa
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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