MUC1 antibody (DTRP (Asp-Thr-Arg-Pro))
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- Target See all MUC1 Antibodies
- MUC1 (Mucin 1 (MUC1))
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Binding Specificity
- DTRP (Asp-Thr-Arg-Pro)
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This MUC1 antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Purification
- Concentrated.
- Immunogen
- Human Milk Fat Globule Membranes
- Clone
- B24-1 (GP1-4)
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product MUC1 Primary Antibody
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- Application Notes
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Immunohistochemistry: (Paraffin/Frozen): 1:50.
Staining Procedure: Prolonged fixation in buffered formalin can destroy the epitope. The antibody may be used at a dilution of 1:50 in IHC. It is recommended that this product be used on frozen tissue sections or specimens. The optimal conditions should be determined by the individual laboratory. - Comment
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Cellular Localization: Cell Membrane, Cytoplasmic.
Recommended Positive Control: Breast Carcinoma - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.3 mg/ml.
- Buffer
- 20 mM Tris-Borate, 150 mM Sodium Chloride, dialyzed media RPMI 1640/D-MEM containing Fetal Bovine Serum, BMC-6 Carrier Polysaccharides, Carrier Protein, pH 7.5
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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Cell membrane-associated mucins and their adhesion-modulating property." in: Trends in biochemical sciences, Vol. 17, Issue 9, pp. 359-63, (1992) (PubMed).
: "Monoclonal antibodies against human milk-fat globule membranes detecting differentiation antigens of the mammary gland and its tumors." in: International journal of cancer. Journal international du cancer, Vol. 34, Issue 2, pp. 197-206, (1984) (PubMed).
: "
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Cell membrane-associated mucins and their adhesion-modulating property." in: Trends in biochemical sciences, Vol. 17, Issue 9, pp. 359-63, (1992) (PubMed).
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- Target
- MUC1 (Mucin 1 (MUC1))
- Alternative Name
- EMA (MUC1 Products)
- Synonyms
- CA 15-3 antibody, CD227 antibody, EMA antibody, H23AG antibody, KL-6 antibody, MAM6 antibody, MCKD1 antibody, MUC-1 antibody, MUC-1/SEC antibody, MUC-1/X antibody, MUC1/ZD antibody, PEM antibody, PEMT antibody, PUM antibody, Muc-1 antibody, mucin 1, cell surface associated antibody, mucin 1, transmembrane antibody, MUC1 antibody, Muc1 antibody
- Background
- Reacts with human high molecular weight sialomucin, episialin, mucin 1 (MUC-1), or polymorphic epithelial mucin (PEM). It recognizes the multiple protein epitope that is relatively insensitive to glycosylation. Therefore, it is very sensitive in the detection of episialin expression in different epithelial tissues.
- Molecular Weight
- 265-400 kDa
- Gene ID
- 4582
- Pathways
- Negative Regulation of intrinsic apoptotic Signaling
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