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GRIN2C antibody (AA 567-595)

GRIN2C Reactivity: Mouse WB Host: Rabbit Polyclonal RB40514 unconjugated
Catalog No. ABIN1881390
  • Target See all GRIN2C Antibodies
    GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))
    Binding Specificity
    • 7
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 567-595
    Reactivity
    • 33
    • 21
    • 19
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Mouse
    Host
    • 45
    • 2
    Rabbit
    Clonality
    • 47
    Polyclonal
    Conjugate
    • 32
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRIN2C antibody is un-conjugated
    Application
    • 33
    • 14
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This GRIN2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 567-595 amino acids from the Central region of human GRIN2C.
    Clone
    RB40514
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GRIN2C Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Need, Keefe, Ge, Grossman, Dickson, McEvoy, Goldstein: "Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis." in: European journal of human genetics : EJHG, Vol. 17, Issue 7, pp. 946-57, (2009) (PubMed).

    Krapivinsky, Krapivinsky, Manasian, Ivanov, Tyzio, Pellegrino, Ben-Ari, Clapham, Medina: "The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1." in: Neuron, Vol. 40, Issue 4, pp. 775-84, (2003) (PubMed).

    Self, Mulholland, Nath, Harris, Prendergast: "The human immunodeficiency virus type-1 transcription factor Tat produces elevations in intracellular Ca2+ that require function of an N-methyl-D-aspartate receptor polyamine-sensitive site." in: Brain research, Vol. 995, Issue 1, pp. 39-45, (2003) (PubMed).

  • Target
    GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))
    Alternative Name
    GRIN2C (GRIN2C Products)
    Synonyms
    GRIN2C antibody, NMDAR2C antibody, il12rb2l antibody, il-12rb2.b antibody, nr2c antibody, GluN2C antibody, NR2C antibody, glutamate ionotropic receptor NMDA type subunit 2C antibody, interleukin 12 receptor, beta 2a, like antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2C S homeolog antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2C antibody, glutamate receptor, ionotropic, NMDA2C (epsilon 3) antibody, GRIN2C antibody, il12rb2l antibody, grin2c.S antibody, grin2c antibody, Grin2c antibody
    Background
    N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq].
    Molecular Weight
    134209
    NCBI Accession
    NP_000826
    UniProt
    Q14957
    Pathways
    Synaptic Membrane
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