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PIGZ antibody (N-Term)

PIGZ Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse, Saccharomyces cerevisiae WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2776579
  • Target See all PIGZ Antibodies
    PIGZ (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Z (PIGZ))
    Binding Specificity
    • 5
    • 1
    N-Term
    Reactivity
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse, Saccharomyces cerevisiae
    Host
    • 8
    Rabbit
    Clonality
    • 8
    Polyclonal
    Conjugate
    • 4
    • 2
    • 1
    • 1
    This PIGZ antibody is un-conjugated
    Application
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    VLWGGLSLLR VLWCLLPQTG YVHPDEFFQS PEVMAEDILG VQAARPWEFY
    Predicted Reactivity
    Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 80%
    Characteristics
    This is a rabbit polyclonal antibody against PIGZ. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PIGZ
    Top Product
    Discover our top product PIGZ Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 579 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Taron, Colussi, Wiedman, Orlean, Taron: "Human Smp3p adds a fourth mannose to yeast and human glycosylphosphatidylinositol precursors in vivo." in: The Journal of biological chemistry, Vol. 279, Issue 34, pp. 36083-92, (2004) (PubMed).

  • Target
    PIGZ (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Z (PIGZ))
    Alternative Name
    PIGZ (PIGZ Products)
    Synonyms
    F630022B06Rik antibody, GPI-MT-IV antibody, PIG-Z antibody, SMP3 antibody, phosphatidylinositol glycan anchor biosynthesis, class Z antibody, phosphatidylinositol glycan anchor biosynthesis class Z antibody, Pigz antibody, PIGZ antibody
    Background
    The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. PIGZ is a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors.The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. This gene encodes a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors.
    Alias Symbols: FLJ12768, GPI-MT-IV, MGC52163, SMP3, PIG-Z
    Protein Size: 579
    Molecular Weight
    63 kDa
    Gene ID
    80235
    NCBI Accession
    NM_025163, NP_079439
    UniProt
    Q86VD9
    Pathways
    Inositol Metabolic Process
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