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FABP3 antibody (Biotin)

FABP3 Reactivity: Human WB, IP, IA Host: Mouse Monoclonal 66E2 Biotin
Catalog No. ABIN2191881
  • Target See all FABP3 Antibodies
    FABP3 (Fatty Acid Binding Protein 3, Muscle and Heart (FABP3))
    Reactivity
    • 104
    • 63
    • 40
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 96
    • 41
    • 1
    Mouse
    Clonality
    • 97
    • 41
    Monoclonal
    Conjugate
    • 64
    • 20
    • 12
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FABP3 antibody is conjugated to Biotin
    Application
    • 87
    • 46
    • 42
    • 18
    • 15
    • 14
    • 13
    • 13
    • 10
    • 9
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunoassay (IA)
    Cross-Reactivity (Details)
    Cross reactivity: Rat H-FABP : Yes, Mouse H-FABP : Yes, Swine H-FABP : Yes, Human B-FABP Average (in ELISA) Human A-FABP : No, Human I-FABP : No, Human L-FABP : No
    Sterility
    0.2 μm filtered
    Clone
    66E2
    Isotype
    IgG1
    Top Product
    Discover our top product FABP3 Primary Antibody
  • Application Notes
    For Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.. Positive Heart cells, or recombinant H-FABP control
    Restrictions
    For Research Use only
  • Buffer
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.
  • Zhen, Berna, Jin, Pritt, Watson, Ackermann, Hale: "Quantification of heart fatty acid binding protein as a biomarker for drug-induced cardiac and musculoskeletal necroses." in: Proteomics. Clinical applications, Vol. 1, Issue 7, pp. 661-71, (2010) (PubMed).

    Zimmermann-Ivol, Burkhard, Le Floch-Rohr, Allard, Hochstrasser, Sanchez: "Fatty acid binding protein as a serum marker for the early diagnosis of stroke: a pilot study." in: Molecular & cellular proteomics : MCP, Vol. 3, Issue 1, pp. 66-72, (2004) (PubMed).

    Pelsers, Hanhoff, Van der Voort, Arts, Peters, Ponds, Honig, Rudzinski, Spener, de Kruijk, Twijnstra, Hermens, Menheere, Glatz: "Brain- and heart-type fatty acid-binding proteins in the brain: tissue distribution and clinical utility." in: Clinical chemistry, Vol. 50, Issue 9, pp. 1568-75, (2004) (PubMed).

    Guillaume, Zimmermann, Burkhard, Hochstrasser, Sanchez: "A potential cerebrospinal fluid and plasmatic marker for the diagnosis of Creutzfeldt-Jakob disease." in: Proteomics, Vol. 3, Issue 8, pp. 1495-9, (2003) (PubMed).

    Roos, Eymann, Symannek, Duppenthaler, Wodzig, Pelsers, Glatz: "Monoclonal antibodies to human heart fatty acid-binding protein." in: Journal of immunological methods, Vol. 183, Issue 1, pp. 149-53, (1995) (PubMed).

  • Target
    FABP3 (Fatty Acid Binding Protein 3, Muscle and Heart (FABP3))
    Alternative Name
    Fatty Acid-Binding Protein, Heart (FABP3 Products)
    Synonyms
    Fabph-1 antibody, Fabph-4 antibody, Fabph1 antibody, Fabph4 antibody, H-FABP antibody, Mdgi antibody, FABP11 antibody, M-FABP antibody, MDGI antibody, O-FABP antibody, FABP antibody, FABP-3 antibody, fabp3 antibody, fatty acid binding protein 3 antibody, fatty acid binding protein 3, muscle and heart antibody, FABP3 antibody, Fabp3 antibody, fabp3 antibody
    Background
    The monoclonal antibody 66E2 recognizes human heart-type fatty acid-binding protein (H-FABP) of both natural and recombinant origin. The H-FABP protein is derived from the human FABP3 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. H-FABP is localized in the heart, skeletal and smooth muscle, mammary epithelial cells, aorta, distal tubules of the kidney, lung, brain, placenta, and ovary. It is also useful as marker for brain damage. Furthermore, this antibody is useful for the purification of H-FABP. Aliases Fatty acid-binding protein 3, FABP3, Muscle fatty acid-binding protein, Mammary-derived growth inhibitor Immunogen Purified human H-FABP
    Pathways
    Monocarboxylic Acid Catabolic Process
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