EPH Receptor B2 antibody (AA 17-200)
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- Target See all EPH Receptor B2 (EPHB2) Antibodies
- EPH Receptor B2 (EPHB2)
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Binding Specificity
- AA 17-200
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This EPH Receptor B2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of EphB2 (aa17-200) expressed in E. coli.
- Clone
- 2D12C6
- Isotype
- IgG2b
- Top Product
- Discover our top product EPHB2 Primary Antibody
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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Altered expression patterns of EphrinB2 and EphB2 in human umbilical vessels and congenital venous malformations." in: Pediatric research, Vol. 57, Issue 4, pp. 537-44, (2005) (PubMed).
: "Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer. ..." in: Nature genetics, Vol. 36, Issue 9, pp. 979-83, (2004) (PubMed).
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Altered expression patterns of EphrinB2 and EphB2 in human umbilical vessels and congenital venous malformations." in: Pediatric research, Vol. 57, Issue 4, pp. 537-44, (2005) (PubMed).
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- Target
- EPH Receptor B2 (EPHB2)
- Alternative Name
- EphB2 (EPHB2 Products)
- Background
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Description: EphB2: EPH receptor B2. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.
Aliases: DRT, ERK, CAPB, Hek5
- Gene ID
- 2048
- HGNC
- 2048
- Pathways
- RTK Signaling, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
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