EPH Receptor A8 antibody (AA 70-150)

Catalog No. ABIN969105

Product Details anti-EPH Receptor A8 Antibody

Target: EPH Receptor A8 (EPHA8)

Binding Specificity: AA 70-150

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor A8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: purified

Immunogen: Purified recombinant fragment of EphA8 (aa70-150) expressed in E. coli.

Clone: 9A12D8

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-EPH Receptor A8 antibody (ABIN969105)

Gu, Shim, Shin, Kim, Park, Han, Park: "The EphA8 receptor induces sustained MAP kinase activation to promote neurite outgrowth in neuronal cells." in: Oncogene, Vol. 24, Issue 26, pp. 4243-56, (2005) (PubMed).

Yamaguchi, Pasquale: "Eph receptors in the adult brain." in: Current opinion in neurobiology, Vol. 14, Issue 3, pp. 288-96, (2004) (PubMed).

Target Details for EPH Receptor A8

Target: EPH Receptor A8 (EPHA8)

Alternative Name: EphA8 (EPHA8 Products)

Background:

Description: EphA8: EPH receptor A8. This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system.

Aliases: EEK, HEK3, KIAA1459, EPHA8

Gene ID: 2046

HGNC: 2046

Pathways: RTK Signaling