LRCH1 antibody (AA 304-333)

Catalog No. ABIN1881505

Product Details anti-LRCH1 Antibody

Target: LRCH1 (Leucine-Rich Repeats and Calponin Homology (CH) Domain Containing 1 (LRCH1))

Binding Specificity: AA 304-333

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRCH1 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LRCH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-333 amino acids from the Central region of human LRCH1.

Clone: RB42699

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-LRCH1 antibody (ABIN1881505)

Zintzaras, Kitsios, Ziogas, Rodopoulou, Karachalios: "Field synopsis and synthesis of genetic association studies in osteoarthritis: the CUMAGAS-OSTEO information system." in: American journal of epidemiology, Vol. 171, Issue 8, pp. 851-8, (2010) (PubMed).

Jiang, Shi, Nakajima, Dai, Wei, Malizos, Qin, Miyamoto, Kamatani, Liu, Tsezou, Nakamura, Ikegawa: "Lack of association of single nucleotide polymorphism in LRCH1 with knee osteoarthritis susceptibility." in: Journal of human genetics, Vol. 53, Issue 1, pp. 42-7, (2007) (PubMed).

Ikegawa: "New gene associations in osteoarthritis: what do they provide, and where are we going?" in: Current opinion in rheumatology, Vol. 19, Issue 5, pp. 429-34, (2007) (PubMed).

Snelling, Sinsheimer, Carr, Loughlin: "Genetic association analysis of LRCH1 as an osteoarthritis susceptibility locus." in: Rheumatology (Oxford, England), Vol. 46, Issue 2, pp. 250-2, (2007) (PubMed).

Spector, Reneland, Mah, Valdes, Hart, Kammerer, Langdown, Hoyal, Atienza, Doherty, Rahman, Nelson, Braun: "Association between a variation in LRCH1 and knee osteoarthritis: a genome-wide single-nucleotide polymorphism association study using DNA pooling." in: Arthritis and rheumatism, Vol. 54, Issue 2, pp. 524-32, (2006) (PubMed).

Target Details for LRCH1

Target: LRCH1 (Leucine-Rich Repeats and Calponin Homology (CH) Domain Containing 1 (LRCH1))

Alternative Name: LRCH1 (LRCH1 Products)

Synonyms: CHDC1 antibody, NP81 antibody, 4832412D13Rik antibody, AI552548 antibody, AW215503 antibody, Chdc1 antibody, mKIAA1016 antibody, leucine rich repeats and calponin homology domain containing 1 antibody, leucine-rich repeats and calponin homology (CH) domain containing 1 antibody, Lrch1 antibody, LRCH1 antibody

Background: This gene encodes a protein with a leucine-rich repeat and a calponin homology domain. Polymorphism in this gene may be associated with susceptibililty to knee osteoarthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 80875

NCBI Accession: NP_001157683, NP_001157685, NP_055931

UniProt: Q9Y2L9