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Interleukin 17a antibody
IL17A
Reactivity: Mouse
Neut
Host: Rat
Monoclonal
TC11-18H10
unconjugated
Product Details anti-Interleukin 17a Antibody
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Target
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Interleukin 17a (IL17A)
(Interleukin 17A (IL17A))
Reactivity
All reactivities for Interleukin 17a antibodies
Mouse
Host
All hosts for Interleukin 17a antibodies
Rat
Clonality
All clonalities for Interleukin 17a antibodies
Monoclonal
Conjugate
All conjugates for Interleukin 17a antibodies
This Interleukin 17a antibody is un-conjugated
Application
All applications for Interleukin 17a antibodies
Neutralization (Neut)
Specificity
Native and recombinant mouse IL-17A.
Purification
Purified from in vitro cultures by protein G affinity chromatography.
Immunogen
Recombinant mouse IL-17
Clone
TC11-18H10
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
Neutralization of mouse IL-17A bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
supplied at 0.5 mg/mL in PBS free of preservatives
Preservative
Without preservative
Storage
4 °C,-20 °C
Storage Comment
Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.
Expiry Date
18 months
References for anti-Interleukin 17a antibody (ABIN6964029)
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He, Li, Yusuf, Elmets, Li, Mountz, Xu : "IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells. " in: Journal of immunology (Baltimore, Md. : 1950) , Vol. 184 , Issue 5 , pp. 2281-8 , (2010 ) (PubMed ).
Mangalam, Luckey, Basal, Jackson, Smart, Rodriguez, David : "HLA-DQ8 (DQB1*0302)-restricted Th17 cells exacerbate experimental autoimmune encephalomyelitis in HLA-DR3-transgenic mice. " in: Journal of immunology (Baltimore, Md. : 1950) , Vol. 182 , Issue 8 , pp. 5131-9 , (2009 ) (PubMed ).
Yen, Cheung, Scheerens, Poulet, McClanahan, McKenzie, Kleinschek, Owyang, Mattson, Blumenschein, Murphy, Sathe, Cua, Kastelein, Rennick : "IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. " in: The Journal of clinical investigation , Vol. 116 , Issue 5 , pp. 1310-6 , (2006 ) (PubMed ).
Target Details for Interleukin 17a
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Target
Interleukin 17a (IL17A)
(Interleukin 17A (IL17A))
Alternative Name
IL17A (IL17A Products )
Synonyms
CTLA8 antibody, IL-17 antibody, IL-17A antibody, IL17 antibody, Ctla-8 antibody, Ctla8 antibody, Il17 antibody, ChIL-17 antibody, IL-17F antibody, IL17A antibody, CTLA-8 antibody, interleukin 17A antibody, IL17A antibody, Il17a antibody
Gene ID
16171
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