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AP2B1 antibody (C-Term)

AP2B1 Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2785455
  • Target See all AP2B1 Antibodies
    AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))
    Binding Specificity
    • 15
    • 8
    • 7
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 60
    • 20
    • 15
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)
    Host
    • 58
    • 2
    Rabbit
    Clonality
    • 58
    • 2
    Polyclonal
    Conjugate
    • 29
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This AP2B1 antibody is un-conjugated
    Application
    • 36
    • 24
    • 13
    • 13
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Sequence
    GAVDLLGGGL DSLLGSDLGG GIGGSPAVGQ SFIPSSVPAT FAPSPTPAVV
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against AP2B1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human AP2B1
    Top Product
    Discover our top product AP2B1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 951 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Schmid, Ford, Burtey, Praefcke, Peak-Chew, Mills, Benmerah, McMahon: "Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly." in: PLoS biology, Vol. 4, Issue 9, pp. e262, (2006) (PubMed).

  • Target
    AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))
    Alternative Name
    AP2B1 (AP2B1 Products)
    Synonyms
    5-HT(2B) antibody, 5-HT2B antibody, ADTB2 antibody, AP105B antibody, AP2-BETA antibody, CLAPB1 antibody, 1300012O03Rik antibody, AI788979 antibody, fa16e07 antibody, wu:fa16c06 antibody, wu:fa16e07 antibody, wu:fc18c08 antibody, zgc:55659 antibody, 5-hydroxytryptamine receptor 2B antibody, adaptor related protein complex 2 beta 1 subunit antibody, adaptor-related protein complex 2, beta 1 subunit antibody, adaptor related protein complex 2 beta 1 subunit L homeolog antibody, HTR2B antibody, AP2B1 antibody, Ap2b1 antibody, ap2b1 antibody, ap2b1.L antibody
    Background
    AP2B1 is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. AP2B1 is found on the cytoplasmic face of coated vesicles in the plasma membrane.The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: ADTB2, AP105B, AP2-BETA, CLAPB1, DKFZp781K0743
    Protein Interaction Partner: NEU4, XRCC6BP1, THAP1, U2AF1, KPNA2, SLC25A6, AFF4, TXN2, PIP5K1C, RAPGEF3, AP1M2, SUMO2, GTF2I, UBC, EGFR, SUMO1, NEDD8, EPHA2, RPA3, RPA2, RPA1, SEC24C, NUSAP1, EPN1, XPO7, PLOD2, LNPEP, GRB2, LDLRAP1, AP2M1, UBD, RNF11, MMS19, ITGA4, FN1, ERBB2, DAB2,
    Protein Size: 951
    Molecular Weight
    105 kDa
    Gene ID
    163
    NCBI Accession
    NM_001030006, NP_001025177
    UniProt
    P63010
    Pathways
    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation
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