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CfPV-2 E7 (N-Term) antibody

Reactivity: Papillomavirus IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN965877
  • Target
    CfPV-2 E7
    Binding Specificity
    N-Term
    Reactivity
    Papillomavirus
    Host
    • 1
    Rabbit
    Clonality
    • 1
    Polyclonal
    Conjugate
    • 1
    Un-conjugated
    Application
    Immunohistochemistry (IHC)
    Immunogen
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of Dog Canine papillomavirus 2 CfPV-2 E7 protein
  • Restrictions
    For Research Use only
  • Storage
    4 °C
  • Yuan, Ghim, Newsome, Apolinario, Olcese, Martin, Delius, Felsburg, Jenson, Schlegel: "An epidermotropic canine papillomavirus with malignant potential contains an E5 gene and establishes a unique genus." in: Virology, Vol. 359, Issue 1, pp. 28-36, (2007) (PubMed).

  • Target
    CfPV-2 E7
    Target Type
    Viral Protein
    Background
    CfPV-2 has unique biological features, it induces papillomas on footpads and interdigital regions which, if infection is persistent, can progress to highly metastatic squamous cell carcinoma. CfPV-2 does not induce oral papillomas in immunocompetent animals and antibodies generated against COPV and CfPV-2 are type-specific. The availability of a new canine papillomavirus with differing genetic and biological properties now makes it possible to study type-specific host immune responses, tissue tropism and the comparative analysis of viral gene functions in the dog.
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