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MLLT1 antibody (C-Term)

MLLT1 Reactivity: Human WB Host: Rabbit Polyclonal RB1927-1928 unconjugated
Catalog No. ABIN390126
  • Target See all MLLT1 Antibodies
    MLLT1 (MLLT1, super elongation complex subunit (MLLT1))
    Binding Specificity
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 523-552, C-Term
    Reactivity
    • 29
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 26
    • 3
    Rabbit
    Clonality
    • 27
    • 2
    Polyclonal
    Conjugate
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    This MLLT1 antibody is un-conjugated
    Application
    • 22
    • 17
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This MLLT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 523-552 amino acids from the C-terminal region of human MLLT1.
    Clone
    RB1927-1928
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:2000. WB: 1:2000. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Bitoun, Oliver, Davies: "The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling." in: Human molecular genetics, Vol. 16, Issue 1, pp. 92-106, (2007) (PubMed).

  • Target
    MLLT1 (MLLT1, super elongation complex subunit (MLLT1))
    Alternative Name
    MLLT1 (MLLT1 Products)
    Synonyms
    MGC84026 antibody, MLLT1 antibody, ENL antibody, LTG19 antibody, YEATS1 antibody, AA407901 antibody, BAM11 antibody, MLLT1, super elongation complex subunit antibody, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 L homeolog antibody, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 antibody, Mllt1 antibody, MLLT1 antibody, mllt1.L antibody, mllt1 antibody
    Background
    Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11,19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.
    Molecular Weight
    62056
    Gene ID
    4298
    NCBI Accession
    NP_005925
    UniProt
    Q03111
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