The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
In PBS (0.05 % BSA, 0.05 % sodium azide)
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
McCoy, Carpenter, Pålsson-McDermott, Gearing, ONeill: "Glucocorticoids inhibit IRF3 phosphorylation in response to Toll-like receptor-3 and -4 by targeting TBK1 activation." in: The Journal of biological chemistry, Vol. 283, Issue 21, pp. 14277-85, (2008) (PubMed).
Péant, Diallo, Lessard, Delvoye, Le Page, Saad, Mes-Masson: "Regulation of IkappaB kinase epsilon expression by the androgen receptor and the nuclear factor-kappaB transcription factor in prostate cancer." in: Molecular cancer research : MCR, Vol. 5, Issue 1, pp. 87-94, (2007) (PubMed).
Aksoy, Albarani, Nguyen, Laes, Ruelle, De Wit, Willems, Goldman, Goriely: "Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells." in: Blood, Vol. 109, Issue 7, pp. 2887-93, (2007) (PubMed).
Sankar, Chan, Romanow, Li, Bates: "IKK-i signals through IRF3 and NFkappaB to mediate the production of inflammatory cytokines." in: Cellular signalling, Vol. 18, Issue 7, pp. 982-93, (2006) (PubMed).
Osterlund, Veckman, Sirén, Klucher, Hiscott, Matikainen, Julkunen: "Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells." in: Journal of virology, Vol. 79, Issue 15, pp. 9608-17, (2005) (PubMed).