PSPH antibody (N-Term)

Catalog No. ABIN1881701

Product Details anti-PSPH Antibody

Target: PSPH (Phosphoserine Phosphatase (PSPH))

Binding Specificity: AA 7-36, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSPH antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PSPH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human PSPH.

Clone: RB42215

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:8000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-PSPH antibody (ABIN1881701)

Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, (2007) (PubMed).

Veiga-da-Cunha, Collet, Prieur, Jaeken, Peeraer, Rabbijns, Van Schaftingen: "Mutations responsible for 3-phosphoserine phosphatase deficiency." in: European journal of human genetics : EJHG, Vol. 12, Issue 2, pp. 163-6, (2004) (PubMed).

Peeraer, Rabijns, Verboven, Collet, Van Schaftingen, De Ranter: "High-resolution structure of human phosphoserine phosphatase in open conformation." in: Acta crystallographica. Section D, Biological crystallography, Vol. 59, Issue Pt 6, pp. 971-7, (2003) (PubMed).

Target Details for PSPH

Target: PSPH (Phosphoserine Phosphatase (PSPH))

Alternative Name: PSPH (PSPH Products)

Background: The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome.

Molecular Weight: 25008

NCBI Accession: NP_004568

UniProt: P78330

Pathways: Warburg Effect