TLR7 antibody (AA 706-728)

Catalog No. ABIN537535

Product Details anti-TLR7 Antibody

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Binding Specificity: AA 706-728

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of TLR7.

Cross-Reactivity: Human, Mouse

Immunogen: A synthetic peptide corresponding to amino acids 706-728 of human TLR7.

Application Details

Application Notes: The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.05 % BSA, 0.05 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-TLR7 antibody (ABIN537535)

Clark, Huang, Murphy, Mollet, Hijnen, Muthukuru, Schanbacher, Edwards, Miller, Kim, Lambert, Kupper: "Human squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cells." in: The Journal of experimental medicine, Vol. 205, Issue 10, pp. 2221-34, (2008) (PubMed).

Palladino, Johnson, Gupta, Chapman, Ojha: "Members of the Toll-like receptor family of innate immunity pattern-recognition receptors are abundant in the male rat reproductive tract." in: Biology of reproduction, Vol. 76, Issue 6, pp. 958-64, (2007) (PubMed).

Brinkmann, Spooner, Hoebe, Beutler, Ploegh, Kim: "The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling." in: The Journal of cell biology, Vol. 177, Issue 2, pp. 265-75, (2007) (PubMed).

Smith, Schwartz, Kawamoto, You, Hwang, Liu, Scherr: "Antitumor effects of imidazoquinolines in urothelial cell carcinoma of the bladder." in: The Journal of urology, Vol. 177, Issue 6, pp. 2347-51, (2007) (PubMed).

Patole, Pawar, Lech, Zecher, Schmidt, Segerer, Ellwart, Henger, Kretzler, Anders: "Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 21, Issue 11, pp. 3062-73, (2006) (PubMed).

Target Details for TLR7

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Alternative Name: TLR7 (TLR7 Products)

Synonyms: TLR7-like antibody, RGD1563357 antibody, toll like receptor 7 antibody, toll-like receptor 7 antibody, TLR7 antibody, Tlr7 antibody

Gene ID: 51284

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades