TPX2 antibody (C-Term)

Catalog No. ABIN2782527

Product Details anti-TPX2 Antibody

Target: TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPX2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LSGSLVQEPF QLATEKRAKE RQELEKRMAE VEAQKAQQLE EARLQEEEQK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TPX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TPX2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 747 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TPX2 antibody (ABIN2782527)

Szczepanowski, Adam-Klages, Kruse, Pollmann, Klapper, Parwaresch, Heidebrecht: "Regulation of repp86 stability by human Siah2." in: Biochemical and biophysical research communications, Vol. 362, Issue 2, pp. 485-90, (2007) (PubMed).

Target Details for TPX2

Target: TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

Alternative Name: TPX2 (TPX2 Products)

Synonyms: C20orf1 antibody, C20orf2 antibody, DIL-2 antibody, DIL2 antibody, FLS353 antibody, GD:C20orf1 antibody, HCA519 antibody, HCTP4 antibody, REPP86 antibody, p100 antibody, 2610005B21Rik antibody, TPX2 antibody, dil-2 antibody, dil2 antibody, hctp4 antibody, repp86 antibody, tpx2 antibody, TPX2, microtubule nucleation factor antibody, TPX2, microtubule-associated antibody, TPX2, microtubule-associated, homolog (Xenopus laevis) antibody, TPX2, microtubule-associated S homeolog antibody, TPX2, microtubule-associated L homeolog antibody, TPX2 antibody, Tpx2 antibody, tpx2.S antibody, tpx2.L antibody

Background: TPX2 binding decreases the size and accessibility of a hydrophobic pocket, adjacent to the ATP site, to inhibitors.
Alias Symbols: C20orf1, C20orf2, DIL-2, DIL2, FLS353, GD:C20orf1, HCA519, HCTP4, REPP86, p100
Protein Interaction Partner: GOLGA2, UBC, RPA3, RPA2, RPA1, LMNA, HDAC9, AURKB, IKBKG, AURKA, IKBKB, CHUK, THAP11, NAP1L1, CDK6, MRPL53, ZNF598, SARNP, THUMPD2, UBE2S, DNAJC8, PPIF, SCAMP3, TWF1, NDUFA7, SERPINH1, SIAH2, HMMR, BRCA1, SUMO2, Mad2l1, KPNB1, KPNA1, FZR1, TPX2,
Protein Size: 747

Molecular Weight: 86 kDa

Gene ID: 22974

NCBI Accession: NM_012112, NP_036244

UniProt: Q9ULW0