AXL antibody (C-Term)

Catalog No. ABIN965631

Product Details anti-AXL Antibody

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AXL antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human AXL(Tyrosine-protein kinase receptor UFO)

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References for anti-AXL antibody (ABIN965631)

Shimojima, Takada, Ebihara, Neumann, Fujioka, Irimura, Jones, Feldmann, Kawaoka: "Tyro3 family-mediated cell entry of Ebola and Marburg viruses." in: Journal of virology, Vol. 80, Issue 20, pp. 10109-16, (2006) (PubMed).

Craven, Xu, Weiner, Fridell, Dent, Srivastava, Varnum, Liu, Cance: "Receptor tyrosine kinases expressed in metastatic colon cancer." in: International journal of cancer. Journal international du cancer, Vol. 60, Issue 6, pp. 791-7, (1995) (PubMed).

Lee, Strunk, Spritz: "A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes." in: Oncogene, Vol. 8, Issue 12, pp. 3403-10, (1993) (PubMed).

Partanen, Mäkelä, Alitalo, Lehväslaiho, Alitalo: "Putative tyrosine kinases expressed in K-562 human leukemia cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 22, pp. 8913-7, (1991) (PubMed).

OBryan, Frye, Cogswell, Neubauer, Kitch, Prokop, Espinosa, Le Beau, Earp, Liu: "axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase." in: Molecular and cellular biology, Vol. 11, Issue 10, pp. 5016-31, (1991) (PubMed).

Janssen, Schulz, Steenvoorden, Schmidberger, Strehl, Ambros, Bartram: "A novel putative tyrosine kinase receptor with oncogenic potential." in: Oncogene, Vol. 6, Issue 11, pp. 2113-20, (1991) (PubMed).

Target Details for AXL

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Alternative Name: AXL (AXL Products)

Synonyms: JTK11 antibody, UFO antibody, AI323647 antibody, Ark antibody, Tyro7 antibody, Ufo antibody, AXL receptor tyrosine kinase antibody, Axl receptor tyrosine kinase antibody, AXL antibody, Axl antibody

Background: AXL(Tyrosine-protein kinase receptor UFO) may function as a signal transducer between specific cell types of mesodermal origin. In case of filovirus infection, AXL seems to function as a cell entry factor. AXL is heterodimer and heterotetramer with GAS6. AXL is a single-pass type I membrane protein. It is highly expressed in metastatic colon tumors. And weakly expressed in normal colon tissue. AXL belongs to the protein kinase superfamily and Tyr protein kinase family and AXL/UFO subfamily. AXL contains 1 protein kinase domain.
Synonyms: UFO

Pathways: RTK Signaling, Cellular Response to Molecule of Bacterial Origin