Prion Protein (PRNP) (AA 106-126) Peptide

Catalog No. ABIN987662

Product Details

Target: PRNP (Prion Protein (PRNP))

Protein Region: AA 106-126

Sequence: One-letter code: KTNMKHMAGA AAAGAVVGGL , Three-letter code: {Lys}{Thr}{Asn}{Met}{Lys}{His}{Met}{Ala}{Gly}{Ala}{Ala}{Ala}{Ala}{Gly}{Ala}{Val}{Val}{Gly}{Gly}{Leu}{Gly

Characteristics: Formula: C₈₀H₁₃₈N₂₆O₂₄S₂

Purity: > 95 %

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Storage: -20 °C

References

Henriques, Pattenden, Aguilar, Castanho: "PrP(106-126) does not interact with membranes under physiological conditions." in: Biophysical journal, Vol. 95, Issue 4, pp. 1877-89, (2008) (PubMed).

Target Details

Target: PRNP (Prion Protein (PRNP))

Synonyms: ASCR Peptide, AltPrP Peptide, CD230 Peptide, CJD Peptide, GSS Peptide, KURU Peptide, PRIP Peptide, PrP Peptide, PrP27-30 Peptide, PrP33-35C Peptide, PrPc Peptide, p27-30 Peptide, Prn Peptide, Prn-p Peptide, prp Peptide, cjd Peptide, prion Peptide, prp(c) Peptide, MGC84114 Peptide, PRP Peptide, PRPC Peptide, Prp Peptide, SIP Peptide, PRNP Peptide, AA960666 Peptide, AI325101 Peptide, PrP Peptide, PrPC Peptide, PrPSc Peptide, Prn-i Peptide, Sinc Peptide, prP27-30 Peptide, prP33-35C Peptide, PrP-1 Peptide, PrP1 Peptide, prnprs1 Peptide, stPrP-1 Peptide, zgc:123004 Peptide, prion protein Peptide, prion protein S homeolog Peptide, prion protein b Peptide, PRNP Peptide, Prnp Peptide, prnp.S Peptide, prnpb Peptide

Background: This peptide increases membrane microviscosity, intracellular Ca2+. Concentration and cell migration in circulating leucocytes, and oxygen production in monocytes and neutrophils. It also induces apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in the GH3 cell lines. PrP (106-126) activates leucocyte migration in a dose-dependent manner. Synonym: PrP (106-126)

Molecular Weight: 1912.3