APLP2
Reactivity: Human
IHC, ELISA
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Tuli, Sharma, McIlhaney, Talmadge, Naslavsky, Caplan, Solheim: "Amyloid precursor-like protein 2 increases the endocytosis, instability, and turnover of the H2-K(d) MHC class I molecule." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 3, pp. 1978-87, (2008) (PubMed).
Target
APLP2
(Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))
HAI antibody, MT-SP1 antibody, MTSP1 antibody, PRSS14 antibody, SNC19 antibody, TADG15 antibody, TMPRSS14 antibody, APLP-2 antibody, APPH antibody, APPL2 antibody, CDEBP antibody, AI790698 antibody, Apph antibody, WALPLP2 antibody, aplp2 B antibody, APLP2 antibody, si:dkey-11k4.3 antibody, aplp2 A antibody, MGC86389 antibody, suppression of tumorigenicity 14 antibody, amyloid beta precursor like protein 2 antibody, amyloid beta (A4) precursor-like protein 2 antibody, amyloid beta (A4) precursor-like protein 2 S homeolog antibody, amyloid beta (A4) precursor-like protein 2 L homeolog antibody, ST14 antibody, APLP2 antibody, Aplp2 antibody, aplp2.S antibody, aplp2 antibody, aplp2.L antibody
Background
APLP2 may play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.Synonyms: APPH, Amyloid protein homolog, Amyloid-like protein 2, CDEBP, CDEI box-binding protein