Melittin (Melt) Peptide

Catalog No. ABIN399605

Product Details

Target: Melittin (Melt)

Purity: > 95 %

Application Details

Restrictions: For Research Use only

Handling

Storage: -20 °C

References

Hood, Jallouk, Campbell, Ratner, Wickline: "Cytolytic nanoparticles attenuate HIV-1 infectivity." in: Antiviral therapy, Vol. 18, Issue 1, pp. 95-103, (2013) (PubMed).

Palm, Medzhitov: "Role of the inflammasome in defense against venoms." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 5, pp. 1809-14, (2013) (PubMed).

Liu, Bian, Sun, Hu, Klemm, Prinz, Rapoport, Hu: "Lipid interaction of the C terminus and association of the transmembrane segments facilitate atlastin-mediated homotypic endoplasmic reticulum fusion." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 32, pp. E2146-54, (2012) (PubMed).

Shaw, Epand, Hsu, Mo, Epand, Yip: "Cationic peptide-induced remodelling of model membranes: direct visualization by in situ atomic force microscopy." in: Journal of structural biology, Vol. 162, Issue 1, pp. 121-38, (2008) (PubMed).

van den Bogaart, Guzmán, Mika, Poolman: "On the mechanism of pore formation by melittin." in: The Journal of biological chemistry, Vol. 283, Issue 49, pp. 33854-7, (2008) (PubMed).

van den Bogaart, Mika, Krasnikov, Poolman: "The lipid dependence of melittin action investigated by dual-color fluorescence burst analysis." in: Biophysical journal, Vol. 93, Issue 1, pp. 154-63, (2007) (PubMed).

Target Details

Target: Melittin (Melt)

Synonyms: Melt Peptide, GB10355 Peptide, melittin Peptide, Melt Peptide

Background: This 26-residue polypeptide isolated from bee venom binds calmodulin in a Ca2+-dependent manner, activates phospholipase A2, and inhibits protein kinase C (IC50=5-7 mM) by binding to the catalytic domain in a Mg-ATP-sensitive manner.

CAS-No: 20449-79-0