Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CD73 antibody (N-Term)

NT5E Reactivity: Human IHC (p) Host: Rabbit Polyclonal RB02844 unconjugated
Catalog No. ABIN388749
  • Target See all CD73 (NT5E) Antibodies
    CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
    Binding Specificity
    • 16
    • 14
    • 13
    • 11
    • 9
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reactivity
    • 111
    • 51
    • 26
    • 18
    • 18
    • 16
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 91
    • 31
    • 9
    • 2
    Rabbit
    Clonality
    • 82
    • 51
    Polyclonal
    Conjugate
    • 58
    • 16
    • 13
    • 9
    • 9
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD73 antibody is un-conjugated
    Application
    • 94
    • 58
    • 52
    • 50
    • 17
    • 16
    • 14
    • 14
    • 14
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This CD73 (NT5E) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CD73 (NT5E).
    Clone
    RB02844
    Isotype
    Ig Fraction
    Top Product
    Discover our top product NT5E Primary Antibody
  • Application Notes
    IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Kim, Piao, Pak, Chung, Han, Hong, Jun, Shim, Choi, Kim: "Umbilical cord mesenchymal stromal cells affected by gestational diabetes mellitus display premature aging and mitochondrial dysfunction." in: Stem cells and development, Vol. 24, Issue 5, pp. 575-86, (2015) (PubMed).

    Doherty, Bai, Hanidziar, Longhi, Lawlor, Putheti, Csizmadia, Nowak, Cheifetz, Moss, Robson: "CD73 is a phenotypic marker of effector memory Th17 cells in inflammatory bowel disease." in: European journal of immunology, Vol. 42, Issue 11, pp. 3062-72, (2012) (PubMed).

    Andrade, Lopez, Noronha, Wink, Borojevic, Margis, Lenz, Battastini, Guma: "Ecto-5'-nucleotidase/CD73 knockdown increases cell migration and mRNA level of collagen I in a hepatic stellate cell line." in: Cell and tissue research, Vol. 344, Issue 2, pp. 279-86, (2011) (PubMed).

    Nadri, Soleimani, Mobarra, Amini: "Expression of dopamine-associated genes on conjunctiva stromal-derived human mesenchymal stem cells." in: Biochemical and biophysical research communications, Vol. 377, Issue 2, pp. 423-8, (2008) (PubMed).

  • Target
    CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
    Alternative Name
    CD73 (NT5E) (NT5E Products)
    Synonyms
    CALJA antibody, CD73 antibody, E5NT antibody, NT antibody, NT5 antibody, NTE antibody, eN antibody, eNT antibody, zgc:63784 antibody, NT5E antibody, MGC114869 antibody, PSPTO2277 antibody, 2210401F01Rik antibody, AI447961 antibody, Nt5 antibody, 5'-nucleotidase ecto antibody, 5'-nucleotidase, ecto (CD73) antibody, 5'-nucleotidase antibody, 5' nucleotidase, ecto antibody, NT5E antibody, nt5e antibody, nt5e.S antibody, PSPTO_2277 antibody, CBU_1233 antibody, MCA1322 antibody, Nt5e antibody
    Background
    Ecto-5-prime-nucleotidase catalyzes conversion at neutral pH of purine 5-prime mononucleotides to nucleosides. The enzyme consists of a dimer of 2 identical 70 kD subunits tethered by a glycosyl phosphatidyl inositol moeity to the exterior plasma membrane surface. The enzyme, a marker of lymphocyte differentiation is associated in deficiency with a variety of immunodeficiency diseases. The preferred substrate is AMP. The NT5 gene has been localized to 6q14-q21 by immunofluorescence and a study of a panel of human x mouse hybrids that contained fragments of chromosome 6 as translocations.
    Molecular Weight
    63368
    Gene ID
    4907
    NCBI Accession
    NP_001191742, NP_002517
    UniProt
    P21589
    Pathways
    Synaptic Membrane, Ribonucleoside Biosynthetic Process
You are here:
Support