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Dynactin 4 antibody (AA 57-298)

DCTN4 Reactivity: Human, Mouse ELISA, WB, IHC, FACS, ICC Host: Mouse Monoclonal 3G9D7 unconjugated
Catalog No. ABIN1724791
  • Target See all Dynactin 4 (DCTN4) Antibodies
    Dynactin 4 (DCTN4)
    Binding Specificity
    • 14
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 57-298
    Reactivity
    • 37
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    Human, Mouse
    Host
    • 35
    • 2
    Mouse
    Clonality
    • 35
    • 2
    Monoclonal
    Conjugate
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Dynactin 4 antibody is un-conjugated
    Application
    • 26
    • 22
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human DCTN4 (AA: 57-298) expressed in E. coli.
    Clone
    3G9D7
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Ayalon, Davis, Scotland, Bennett: "An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan." in: Cell, Vol. 135, Issue 7, pp. 1189-200, (2008) (PubMed).

    Lim, Cater, Mercer, La Fontaine: "Copper-dependent interaction of dynactin subunit p62 with the N terminus of ATP7B but not ATP7A." in: The Journal of biological chemistry, Vol. 281, Issue 20, pp. 14006-14, (2006) (PubMed).

  • Target
    Dynactin 4 (DCTN4)
    Alternative Name
    DCTN4 (DCTN4 Products)
    Synonyms
    DYN4 antibody, P62 antibody, MGC84654 antibody, zgc:112431 antibody, MGC97564 antibody, 1110001K06Rik antibody, 4930547K17Rik antibody, C130039E17Rik antibody, p62 antibody, dynactin subunit 4 antibody, dynactin subunit 4 L homeolog antibody, dynactin 4 antibody, dynactin 4, putative antibody, DCTN4 antibody, Dctn4 antibody, dctn4.L antibody, dctn4 antibody, PKH_031720 antibody
    Background

    Description: Dynactin 4 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.The dynactin complex binds cargo, such as vesicles and organelles, to cytoplasmic dynein for retrograde microtubule-mediated trafficking and could feasibly be involved in the copper-regulated trafficking of ATP7B. , ,

    Aliases: P62, DYN4

    Molecular Weight
    52.3 kDa
    Gene ID
    51164
    HGNC
    51164
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