×
For best experience we recommend to activate Javascript in your browser.
CDKN1B antibody (AA 8-12)
CDKN1B
Reactivity: Human, Mouse, Rat
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CDKN1B Antibody
(hide)
Target
See all CDKN1B Antibodies
CDKN1B
(Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
Binding Specificity
All epitopes for CDKN1B antibodies
AA 8-12
Reactivity
All reactivities for CDKN1B antibodies
Human, Mouse, Rat
Host
All hosts for CDKN1B antibodies
Rabbit
Clonality
All clonalities for CDKN1B antibodies
Polyclonal
Conjugate
All conjugates for CDKN1B antibodies
This CDKN1B antibody is un-conjugated
Application
All applications for CDKN1B antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Specificity
The antibody detects endogenous level of total p27Kip1 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
Peptide sequence around AA 8-12 (N-G-S-P-S) derived from Human p27Kip1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Isotype
IgG
Top Product
Discover our top product CDKN1B Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
Western blotting: 1:500-1:1000 Immunohistochemistry: 1:50-1:100
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
References for anti-CDKN1B antibody (ABIN362757)
(hide)
Yang, Xu, Li, Duan, Fu, Zhang, Zhao, Qiao, Chen, Geng, Che, Cao, Wang, Zhang, Long, He, Cui, Chen, Wang, Liu : "Cloning and characterization of a novel intracellular protein p48.2 that negatively regulates cell cycle progression. " in: The international journal of biochemistry & cell biology , Vol. 41 , Issue 11 , pp. 2240-50 , (2009 ) (PubMed ).
Target Details for CDKN1B
(hide)
Target
CDKN1B
(Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
Alternative Name
p27Kip1 (CDKN1B Products )
Synonyms
CDKN4 antibody, KIP1 antibody, MEN1B antibody, MEN4 antibody, P27KIP1 antibody, cdkn1b antibody, sb:cb611 antibody, wu:fb63g10 antibody, wu:fb64g10 antibody, wu:fe18e03 antibody, CDKN1B antibody, Kip1 antibody, p27 antibody, FAM14D antibody, ISG12 antibody, ISG12A antibody, P27 antibody, Cdki1b antibody, AA408329 antibody, AI843786 antibody, p27Kip1 antibody, cdkn1bl antibody, cyclin dependent kinase inhibitor 1B antibody, cyclin-dependent kinase inhibitor 1Bb antibody, interferon alpha inducible protein 27 antibody, cyclin-dependent kinase inhibitor 1B antibody, cyclin-dependent kinase inhibitor 1Ba antibody, CDKN1B antibody, cdkn1bb antibody, IFI27 antibody, Cdkn1b antibody, cdkn1ba antibody
Background
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events.
Molecular Weight
27 kDa
NCBI Accession
NP_004055
UniProt
P46527
Pathways
Cell Division Cycle , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Positive Regulation of Peptide Hormone Secretion , Negative Regulation of Hormone Secretion , Sensory Perception of Sound , Mitotic G1-G1/S Phases , DNA Replication , Positive Regulation of Endopeptidase Activity , Synthesis of DNA , Autophagy
Recently viewed
(hide)