FKBP1A Protein (AA 1-108) (GST tag)

Catalog No. ABIN1354116

Product Details

Target: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Protein Type: Recombinant

Protein Characteristics: AA 1-108

Origin: Human

Source: Wheat germ

Purification tag / Conjugate: This FKBP1A protein is labelled with GST tag.

Application: Western Blotting (WB), ELISA, Antibody Array (AA), Affinity Purification (AP)

Purpose: FKBP1A (Human) Recombinant Protein (P01)

Sequence: MGVQVETISP GDGRTFPKRG QTCVVHYTGM LEDGKKFDSS RDRNKPFKFM LGKQEVIRGW EEGVAQMSVG QRAKLTISPD YAYGATGHPG IIPPHATLVF DVELLKLE

Characteristics: Human FKBP1A full-length ORF ( AAH05147, 1 a.a. - 108 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Handling

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Storage Comment: Best use within three months from the date of receipt of this protein.

References

Åström-Olsson, Li, Olofsson, Borén, Öhlin, Grip: "Impact of hypoxia, simulated ischemia and reperfusion in HL-1 cells on the expression of FKBP12/FKBP12.6 and intracellular calcium dynamics." in: Biochemical and biophysical research communications, Vol. 422, Issue 4, pp. 732-8, (2012) (PubMed).

Madeira, Ohman, Nilsson, Sjögren, Andrén, Svenningsson: "Coupling surface plasmon resonance to mass spectrometry to discover novel protein-protein interactions." in: Nature protocols, Vol. 4, Issue 7, pp. 1023-37, (2009) (PubMed).

Nilsson, Sköld, Sjögren, Svensson, Pierson, Zhang, Caprioli, Buijs, Persson, Svenningsson, Andrén: "Increased striatal mRNA and protein levels of the immunophilin FKBP-12 in experimental Parkinson's disease and identification of FKBP-12-binding proteins." in: Journal of proteome research, Vol. 6, Issue 10, pp. 3952-61, (2007) (PubMed).

Target Details

Target: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Alternative Name: FKBP1A (FKBP1A Products)

Synonyms: 12kDa Protein, FKBP12 Protein, FKBP12-T1 Protein, FKBP12-T2 Protein, Fkbp Protein, Fkbp1 Protein, mFKBP1 Protein, mFKBP12 Protein, FKBP-12 Protein, FKBP-1A Protein, FKBP1 Protein, Rotamase Protein, Fkbp12 Protein, ARABIDOPSIS THALIANA FK506-BINDING PROTEIN 12 Protein, ATFKBP12 Protein, FK506-binding protein 12 Protein, IMMUNOPHILIN Protein, MSJ1.19 Protein, MSJ1_19 Protein, PKC12 Protein, PKCI2 Protein, PPIASE Protein, FKBP1B Protein, Fkbp2 Protein, fj02g10 Protein, zgc:73373 Protein, wu:fj02g10 Protein, FKBP1A Protein, Bmfkbp13 Protein, zgc:103752 Protein, FK506 binding protein 1a Protein, FK506 binding protein 1A Protein, FK506-binding protein Protein, FK506-binding protein 12 Protein, FK506 binding protein 1Aa Protein, FK506 binding protein 1C Protein, FK506-binding protein 59 Protein, FK506 binding protein like Protein, FK506 binding protein 1A L homeolog Protein, FK506 binding protein 1Ab Protein, Fkbp1a Protein, FKBP1A Protein, Fkbp12 Protein, FKBP12 Protein, fkbp1aa Protein, FKBP1C Protein, EHI_180160 Protein, LOC5573443 Protein, Fkbp13 Protein, FKBPL Protein, fkbp1a.L Protein, fkbp1ab Protein

Background: Full Gene Name: FK506 binding protein 1A, 12 kDa
Synonyms: FKBP-12,FKBP1,FKBP12,FKBP12C,PKC12,PKCI2,PPIASE

Gene ID: 2280

Pathways: Negative Regulation of Transporter Activity, Methionine Biosynthetic Process