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KCNMB2 antibody (N-Term)

KCNMB2 Reactivity: Human WB Host: Rabbit Polyclonal RB42799 unconjugated
Catalog No. ABIN1881476
  • Target See all KCNMB2 Antibodies
    KCNMB2 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 2 (KCNMB2))
    Binding Specificity
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reactivity
    • 35
    • 21
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 35
    • 2
    Rabbit
    Clonality
    • 35
    • 2
    Polyclonal
    Conjugate
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KCNMB2 antibody is un-conjugated
    Application
    • 29
    • 20
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This KCNMB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KCNMB2.
    Clone
    RB42799
    Isotype
    Ig Fraction
    Top Product
    Discover our top product KCNMB2 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Treviño, Yang, French, Hunger, Carroll, Devidas, Willman, Neale, Downing, Raimondi, Pui, Evans, Relling: "Germline genomic variants associated with childhood acute lymphoblastic leukemia." in: Nature genetics, Vol. 41, Issue 9, pp. 1001-5, (2009) (PubMed).

    Lee, Cui: "{beta} subunit-specific modulations of BK channel function by a mutation associated with epilepsy and dyskinesia." in: The Journal of physiology, Vol. 587, Issue Pt 7, pp. 1481-98, (2009) (PubMed).

    Zarei, Song, Wilson, Cox, Colom, Knaus, Stefani, Toro: "Endocytic trafficking signals in KCNMB2 regulate surface expression of a large conductance voltage and Ca(2+)-activated K+ channel." in: Neuroscience, Vol. 147, Issue 1, pp. 80-9, (2007) (PubMed).

    Zeng, Benzinger, Xia, Lingle: "BK channels with beta3a subunits generate use-dependent slow afterhyperpolarizing currents by an inactivation-coupled mechanism." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 17, pp. 4707-15, (2007) (PubMed).

    Orio, Torres, Rojas, Carvacho, Garcia, Toro, Valverde, Latorre: "Structural determinants for functional coupling between the beta and alpha subunits in the Ca2+-activated K+ (BK) channel." in: The Journal of general physiology, Vol. 127, Issue 2, pp. 191-204, (2006) (PubMed).

  • Target
    KCNMB2 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 2 (KCNMB2))
    Alternative Name
    KCNMB2 (KCNMB2 Products)
    Synonyms
    KCNMB3 antibody, zgc:101842 antibody, KCNMB2 antibody, 2700049B16Rik antibody, 3110031N04Rik antibody, Kcmb2 antibody, potassium calcium-activated channel subfamily M regulatory beta subunit 2 antibody, potassium large conductance calcium-activated channel, subfamily M, beta member 2 antibody, KCNMB2 antibody, kcnmb2 antibody, Kcnmb2 antibody
    Background
    MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Two variants encoding the same protein have been found for this gene. [provided by RefSeq].
    Molecular Weight
    27130
    NCBI Accession
    NP_001265840, NP_005823, NP_852006
    UniProt
    Q9Y691
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