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APOE antibody (C-Term)

APOE Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB15180 unconjugated
Catalog No. ABIN391849
  • Target See all APOE Antibodies
    APOE (Apolipoprotein E (APOE))
    Binding Specificity
    • 15
    • 15
    • 15
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 263-292, C-Term
    Reactivity
    • 101
    • 74
    • 56
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 102
    • 22
    • 13
    • 2
    Rabbit
    Clonality
    • 104
    • 34
    Polyclonal
    Conjugate
    • 59
    • 18
    • 12
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    This APOE antibody is un-conjugated
    Application
    • 110
    • 57
    • 39
    • 39
    • 30
    • 24
    • 20
    • 12
    • 10
    • 9
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    Pr, Rb
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This APOE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human APOE.
    Clone
    RB15180
    Isotype
    Ig Fraction
    Top Product
    Discover our top product APOE Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Benga, Krieger, Dimitrova, Zeisel, Parnot, Lupberger, Hildt, Luo, McLauchlan, Baumert, Schuster: "Apolipoprotein E interacts with hepatitis C virus nonstructural protein 5A and determines assembly of infectious particles." in: Hepatology (Baltimore, Md.), Vol. 51, Issue 1, pp. 43-53, (2009) (PubMed).

  • Target
    APOE (Apolipoprotein E (APOE))
    Alternative Name
    APOE (APOE Products)
    Synonyms
    ad2 antibody, apoprotein antibody, im:7036787 antibody, wu:fb69a05 antibody, zgc:110064 antibody, apoe antibody, AI255918 antibody, AD2 antibody, LDLCQ5 antibody, LPG antibody, APOEA antibody, Apo-E antibody, apolipoprotein E antibody, apolipoprotein Ea antibody, apoe antibody, apoea antibody, Apoe antibody, APOE antibody
    Background
    Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III),in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
    Molecular Weight
    36154
    Gene ID
    348
    NCBI Accession
    NP_000032
    UniProt
    P02649
    Pathways
    Regulation of Cell Size, Lipid Metabolism
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