Cyclin B2 antibody (pSer392)

Catalog No. ABIN1881161

Product Details anti-Cyclin B2 Antibody

Target: Cyclin B2 (CCNB2)

Binding Specificity: pSer392

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin B2 antibody is un-conjugated

Application: Dot Blot (DB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This mouse CCNB2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S392 of mouse CCNB2.

Clone: RB42081

Isotype: Ig Fraction

Application Details

Application Notes: DB: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-Cyclin B2 antibody (ABIN1881161)

Risley, Clowes, Yu, Mitchell, Hentges: "The Mediator complex protein Med31 is required for embryonic growth and cell proliferation during mammalian development." in: Developmental biology, Vol. 342, Issue 2, pp. 146-56, (2010) (PubMed).

Wu, Zhang, Huang, Yang, Hua: "Regulation of cyclin B2 expression and cell cycle G2/m transition by menin." in: The Journal of biological chemistry, Vol. 285, Issue 24, pp. 18291-300, (2010) (PubMed).

De Martino, Visone, Wierinckx, Palmieri, Ferraro, Cappabianca, Chiappetta, Forzati, Lombardi, Colao, Trouillas, Fedele, Fusco: "HMGA proteins up-regulate CCNB2 gene in mouse and human pituitary adenomas." in: Cancer research, Vol. 69, Issue 5, pp. 1844-50, (2009) (PubMed).

Kawaguchi, Ikawa, Kasukawa, Ueda, Kurimoto, Saitou, Matsuzaki: "Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis." in: Development (Cambridge, England), Vol. 135, Issue 18, pp. 3113-24, (2008) (PubMed).

Fogel, Chiang, Huang, Agarwala: "Ventral specification and perturbed boundary formation in the mouse midbrain in the absence of Hedgehog signaling." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 237, Issue 5, pp. 1359-72, (2008) (PubMed).

Target Details for Cyclin B2

Target: Cyclin B2 (CCNB2)

Alternative Name: CCNB2 (CCNB2 Products)

Synonyms: HsT17299 antibody, CycB2 antibody, sb:cb303 antibody, cycB2 antibody, LOC100136691 antibody, C-B2 antibody, cyclinb2 antibody, hst17299 antibody, LOC100282653 antibody, cyclin B2 antibody, cyclin B2 S homeolog antibody, CCNB2 antibody, Ccnb2 antibody, ccnb2 antibody, LOC100136691 antibody, LOC100282653 antibody, ccnb2.S antibody

Background: Essential for the control of the cell cycle at the G2/M (mitosis) transition.

Molecular Weight: 45383

NCBI Accession: NP_031656

UniProt: P30276

Pathways: Cell Division Cycle, M Phase