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FXR1 antibody (N-Term)

FXR1 Reactivity: Mouse WB Host: Rabbit Polyclonal RB41819 unconjugated
Catalog No. ABIN1881357
  • Target See all FXR1 Antibodies
    FXR1 (Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))
    Binding Specificity
    • 13
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 37-66, N-Term
    Reactivity
    • 40
    • 39
    • 23
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 49
    • 3
    • 1
    Rabbit
    Clonality
    • 48
    • 5
    Polyclonal
    Conjugate
    • 25
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FXR1 antibody is un-conjugated
    Application
    • 49
    • 28
    • 10
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    B, Ha, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This FXR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human FXR1.
    Clone
    RB41819
    Isotype
    Ig Fraction
    Top Product
    Discover our top product FXR1 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Coffee, Tessier, Woodruff, Broadie: "Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P." in: Disease models & mechanisms, Vol. 3, Issue 7-8, pp. 471-85, (2010) (PubMed).

    Darnell, Fraser, Mostovetsky, Darnell: "Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs." in: Human molecular genetics, Vol. 18, Issue 17, pp. 3164-77, (2009) (PubMed).

    Purcell, Wray, Stone, Visscher, ODonovan, Sullivan, Sklar: "Common polygenic variation contributes to risk of schizophrenia and bipolar disorder." in: Nature, Vol. 460, Issue 7256, pp. 748-52, (2009) (PubMed).

    Davidovic, Sacconi, Bechara, Delplace, Allegra, Desnuelle, Bardoni: "Alteration of expression of muscle specific isoforms of the fragile X related protein 1 (FXR1P) in facioscapulohumeral muscular dystrophy patients." in: Journal of medical genetics, Vol. 45, Issue 10, pp. 679-85, (2008) (PubMed).

    Vasudevan, Steitz: "AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2." in: Cell, Vol. 128, Issue 6, pp. 1105-18, (2007) (PubMed).

  • Target
    FXR1 (Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))
    Alternative Name
    FXR1 (FXR1 Products)
    Synonyms
    FXR1P antibody, wu:fb16f11 antibody, wu:fd18c10 antibody, zgc:66226 antibody, Fxr1h antibody, Fxr1p antibody, XtFxr1p antibody, fxr1h antibody, xFxr1p antibody, FXR1 antibody, 1110050J02Rik antibody, 9530073J07Rik antibody, AI851072 antibody, xfxr1 antibody, fxr1 antibody, FMR1 autosomal homolog 1 antibody, fragile X mental retardation, autosomal homolog 1 antibody, fragile X mental retardation gene 1, autosomal homolog antibody, FMR1 autosomal homolog 1 L homeolog antibody, FMR1 autosomal homolog 1 S homeolog antibody, FXR1 antibody, fxr1 antibody, Fxr1 antibody, fxr1.L antibody, fxr1.S antibody
    Background
    The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    69721
    NCBI Accession
    NP_001013456, NP_001013457, NP_005078
    UniProt
    P51114
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