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PDK3 antibody (N-Term)

PDK3 Reactivity: Human WB Host: Rabbit Polyclonal RB3039 unconjugated
Catalog No. ABIN391038
  • Target See all PDK3 Antibodies
    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
    Binding Specificity
    • 13
    • 9
    • 9
    • 9
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reactivity
    • 36
    • 32
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 55
    • 3
    Rabbit
    Clonality
    • 55
    • 3
    Polyclonal
    Conjugate
    • 30
    • 7
    • 6
    • 5
    • 5
    • 5
    This PDK3 antibody is un-conjugated
    Application
    • 51
    • 41
    • 21
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PDK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PDK3.
    Clone
    RB3039
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PDK3 Primary Antibody
  • Application Notes
    WB: 1:1000. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Halim, Mcfate, Mohyeldin, Okagaki, Korotchkina, Patel, Jeoung, Harris, Schell, Verma: "Phosphorylation status of pyruvate dehydrogenase distinguishes metabolic phenotypes of cultured rat brain astrocytes and neurons." in: Glia, Vol. 58, Issue 10, pp. 1168-76, (2010) (PubMed).

    McFate, Mohyeldin, Lu, Thakar, Henriques, Halim, Wu, Schell, Tsang, Teahan, Zhou, Califano, Jeoung, Harris, Verma: "Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells." in: The Journal of biological chemistry, Vol. 283, Issue 33, pp. 22700-8, (2008) (PubMed).

  • Target
    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
    Alternative Name
    PDK3 (PDK3 Products)
    Synonyms
    pdk3 antibody, PDK3 antibody, 2610001M10Rik antibody, AI035637 antibody, zgc:158702 antibody, pyruvate dehydrogenase kinase 3 antibody, pyruvate dehydrogenase kinase, isozyme 3a antibody, pyruvate dehydrogenase kinase, isoenzyme 3 antibody, fragile site, 5-azacytidine type, common, fra(1)(q12) antibody, pyruvate dehydrogenase kinase, isozyme 3b antibody, PDK3 antibody, Pdk3 antibody, pdk3a antibody, pdk3 antibody, FRA1J antibody, pdk3b antibody
    Background
    PDK3 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
    Molecular Weight
    46939
    Gene ID
    5165
    NCBI Accession
    NP_001135858, NP_005382
    UniProt
    Q15120
    Pathways
    PI3K-Akt Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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