CNBP antibody (AA 91-118)

Catalog No. ABIN1881216

Product Details anti-CNBP Antibody

Target: CNBP (CCHC-Type Zinc Finger, Nucleic Acid Binding Protein (CNBP))

Binding Specificity: AA 91-118

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: B, C, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CNBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-118 amino acids from the Central region of human CNBP.

Clone: RB43101

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-CNBP antibody (ABIN1881216)

Catalli, Morgante, Iraci, Rinaldi, Botta, Novelli: "Validation of sensitivity and specificity of tetraplet-primed PCR (TP-PCR) in the molecular diagnosis of myotonic dystrophy type 2 (DM2)." in: The Journal of molecular diagnostics : JMD, Vol. 12, Issue 5, pp. 601-6, (2010) (PubMed).

Massa, Panico, Caldarola, Fusco, Sabatelli, Terracciano, Botta, Novelli, Bernardi, Loreni: "The myotonic dystrophy type 2 (DM2) gene product zinc finger protein 9 (ZNF9) is associated with sarcomeres and normally localized in DM2 patients' muscles." in: Neuropathology and applied neurobiology, Vol. 36, Issue 4, pp. 275-84, (2010) (PubMed).

Auvinen, Suominen, Hannonen, Bachinski, Krahe, Udd: "Myotonic dystrophy type 2 found in two of sixty-three persons diagnosed as having fibromyalgia." in: Arthritis and rheumatism, Vol. 58, Issue 11, pp. 3627-31, (2008) (PubMed).

Panayiotopoulos, Scarpalezos: "Dystrophia myotonica. Peripheral nerve involvement and pathogenetic implications." in: Journal of the neurological sciences, Vol. 27, Issue 1, pp. 1-16, (1976) (PubMed).

Target Details for CNBP

Target: CNBP (CCHC-Type Zinc Finger, Nucleic Acid Binding Protein (CNBP))

Alternative Name: CNBP (CNBP Products)

Background: This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 19463

NCBI Accession: NP_001120664, NP_001120665, NP_001120666, NP_001120668, NP_003409

UniProt: P62633