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BRMS1 antibody (AA 1-246)

BRMS1 Reactivity: Human WB, ELISA, IP Host: Mouse Monoclonal 2D4-2G11 unconjugated
Catalog No. ABIN565191
  • Target See all BRMS1 Antibodies
    BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
    Binding Specificity
    • 15
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-246
    Reactivity
    • 46
    • 26
    • 25
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 45
    • 1
    Mouse
    Clonality
    • 45
    • 1
    Monoclonal
    Conjugate
    • 21
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BRMS1 antibody is un-conjugated
    Application
    • 44
    • 20
    • 13
    • 13
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    Purpose
    Mouse monoclonal antibody raised against a full length recombinant BRMS1.
    Sequence
    MPVQPPSKDT EEMEAEGDSA AEMNGEEEES EEERSGSQTE SEEESSEMDD EDYERRRSEC VSEMLDLEKQ FSELKEKLFR ERLSQLRLRL EEVGAERAPE YTEPLGGLQR SLKIRIQVAG IYKGFCLDVI RNKYECELQG AKQHLESEKL LLYDTLQGEL QERIQRLEED RQSLDLSSEW WDDKLHARGS SRSWDSLPPS KRKKAPLVSG PYIVYMLQEI DILEDWTAIK KARAAVSPQK RKSDGP
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    BRMS1 (AAH09834, 1 a.a. ~ 246 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    2D4-2G11
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Ventura, Quezada, Maloney, Fernandes, Antecka, Martins, Bakalian, di Cesare, Burnier: "Expression of the metastasis suppressor BRMS1 in uveal melanoma." in: Ecancermedicalscience, Vol. 8, pp. 410, (2014) (PubMed).

    Liu, Mayo, Nagji, Hall, Shock, Xiao, Stelow, Jones: "BRMS1 suppresses lung cancer metastases through an E3 ligase function on histone acetyltransferase p300." in: Cancer research, Vol. 73, Issue 4, pp. 1308-17, (2013) (PubMed).

    Cui, Liu, He, Li, Huang, Sun, Tang, Chen, Jiang, Chen, Yun, Zeng, Guo, Wang, Ma: "Low BRMS1 expression promotes nasopharyngeal carcinoma metastasis in vitro and in vivo and is associated with poor patient survival." in: BMC cancer, Vol. 12, pp. 376, (2012) (PubMed).

    Kim, Nam, Pyo, Jang, Kim, Kim, Boo, Lee, Yoon, Baek, Kim: "Breast cancer metastasis suppressor 1 (BRMS1) is destabilized by the Cul3-SPOP E3 ubiquitin ligase complex." in: Biochemical and biophysical research communications, Vol. 415, Issue 4, pp. 720-6, (2011) (PubMed).

    Nagji, Liu, Stelow, Stukenborg, Jones: "BRMS1 transcriptional repression correlates with CpG island methylation and advanced pathological stage in non-small cell lung cancer." in: The Journal of pathology, Vol. 221, Issue 2, pp. 229-37, (2010) (PubMed).

    Smith, Liu, Siefert, Moskaluk, Petroni, Jones: "Breast cancer metastasis suppressor 1 (BRMS1) suppresses metastasis and correlates with improved patient survival in non-small cell lung cancer." in: Cancer letters, Vol. 276, Issue 2, pp. 196-203, (2009) (PubMed).

    Rivera, Megias, Bravo: "Proteomics-based strategy to delineate the molecular mechanisms of the metastasis suppressor gene BRMS1." in: Journal of proteome research, Vol. 6, Issue 10, pp. 4006-18, (2007) (PubMed).

    Liu, Smith, Jones: "Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis." in: Molecular and cellular biology, Vol. 26, Issue 23, pp. 8683-96, (2006) (PubMed).

  • Target
    BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
    Alternative Name
    BRMS1 (BRMS1 Products)
    Synonyms
    MGC98869 antibody, BRMS1 antibody, BRMS1L antibody, AV003220 antibody, AW554636 antibody, si:zc188c22.3 antibody, si:zc194c5.2 antibody, wu:fb57b08 antibody, zgc:56414 antibody, breast cancer metastasis suppressor 1 antibody, breast cancer metastasis-suppressor 1 antibody, breast cancer metastasis suppressor 1 L homeolog antibody, BRMS1 antibody, Brms1 antibody, brms1.L antibody, brms1 antibody
    Background
    Full Gene Name: breast cancer metastasis suppressor 1
    Synonyms: DKFZp564A063
    Gene ID
    25855
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