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Dynamin 1-Like Protein (DNM1L) (AA 1-710) (GST tag)

DNM1L Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Catalog No. ABIN1351855
  • Target See all Dynamin 1-Like (DNM1L) Proteins
    Dynamin 1-Like (DNM1L)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-710
    Origin
    • 5
    • 2
    • 2
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    Wheat germ
    Purification tag / Conjugate
    This Dynamin 1-Like protein is labelled with GST tag.
    Application
    ELISA, Western Blotting (WB), Antibody Array (AA), Affinity Purification (AP)
    Purpose
    DNM1L (Human) Recombinant Protein (P01)
    Sequence
    MEALIPVINK LQDVFNTVGA DIIQLPQIVV VGTQSSGKSS VLESLVGRDL LPRGTGIVTR RPLILQLVHV SQEDKRKTTG EENGVEAEEW GKFLHTKNKL YTDFDEIRQE IENETERISG NNKGVSPEPI HLKIFSPNVV NLTLVDLPGM TKVPVGDQPK DIELQIRELI LRFISNPNSI ILAVTAANTD MATSEALKIS REVDPDGRRT LAVITKLDLM DAGTDAMDVL MGRVIPVKLG IIGVVNRSQL DINNKKSVTD SIRDEYAFLQ KKYPSLANRN GTKYLARTLN RLLMHHIRDC LPELKTRINV LAAQYQSLLN SYGEPVDDKS ATLLQLITKF ATEYCNTIEG TAKYIETSEL CGGARICYIF HETFGRTLES VDPLGGLNTI DILTAIRNAT GPRPALFVPE VSFELLVKRQ IKRLEEPSLR CVELVHEEMQ RIIQHCSNYS TQELLRFPKL HDAIVEVVTC LLRKRLPVTN EMVHNLVAIE LAYINTKHPD FADACGLMNN NIEEQRRNRL ARELPSAVSR DKLIQDSRRE TKNVASGGGG VGDGVQEPTT GNWRGMLKTS KAEELLAEEK SKPIPIMPAS PQKGHAVNLL DVPVPVARKL SAREQRDCEV IERLIKSYFL IVRKNIQDSV PKAVMHFLVN HVKDTLQSEL VGQLYKSSLL DDLLTESEDM AQRRKEAADM LKALQGASQI IAEIRETHLW
    Characteristics
    Human DNM1L full-length ORF ( AAH24590.1, 1 a.a. - 710 a.a.) recombinant protein with GST-tag at N-terminal.
    Purification
    in vitro wheat germ expression system
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Preparation method: in vitro, wheat germ expression system
    Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

    Restrictions
    For Research Use only
  • Buffer
    50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -80 °C
    Storage Comment
    Best use within three months from the date of receipt of this protein.
  • Qi, Qvit, Su, Mochly-Rosen: "A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity." in: Journal of cell science, Vol. 126, Issue Pt 3, pp. 789-802, (2013) (PubMed).

    Su, Qi: "Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation." in: Human molecular genetics, Vol. 22, Issue 22, pp. 4545-61, (2013) (PubMed).

    Guo, Disatnik, Monbureau, Shamloo, Mochly-Rosen, Qi: "Inhibition of mitochondrial fragmentation diminishes Huntington's disease-associated neurodegeneration." in: The Journal of clinical investigation, Vol. 123, Issue 12, pp. 5371-88, (2013) (PubMed).

    Qi, Disatnik, Shen, Sobel, Mochly-Rosen: "Aberrant mitochondrial fission in neurons induced by protein kinase C{delta} under oxidative stress conditions in vivo." in: Molecular biology of the cell, Vol. 22, Issue 2, pp. 256-65, (2011) (PubMed).

  • Target
    Dynamin 1-Like (DNM1L)
    Alternative Name
    DNM1L (DNM1L Products)
    Synonyms
    DLP1 Protein, DRP1 Protein, DVLP Protein, DYMPLE Protein, EMPF Protein, HDYNIV Protein, 6330417M19Rik Protein, AI450666 Protein, Dlp1 Protein, Dnmlp1 Protein, Drp1 Protein, python Protein, Dnml1 Protein, dnm1l Protein, MGC53850 Protein, zgc:66163 Protein, DNM1L Protein, 18.m06247 Protein, CG3210 Protein, DRP Protein, Dmel\CG3210 Protein, Dnm1/Drp1 Protein, Drp Protein, Drp-1 Protein, drp-1 Protein, drp1 Protein, frat Protein, l(2)22Fc Protein, l(2)22Fd Protein, l(2)ND2 Protein, l(2)ND3 Protein, dynamin 1 like Protein, dynamin 1-like Protein, dynamin 1-like L homeolog Protein, dynamin-1-like Protein, dynamin-1-like protein Protein, dynamin-like protein Protein, Dynamin related protein 1 Protein, DNM1L Protein, Dnm1l Protein, dnm1l.L Protein, dnm1l Protein, LOC100369408 Protein, LOC411472 Protein, dyn1 Protein, cgd1_580 Protein, EHI_052740 Protein, PVX_092875 Protein, BBOV_II002980 Protein, Drp1 Protein
    Background
    Full Gene Name: dynamin 1-like
    Synonyms: DLP1,DRP1,DVLP,DYMPLE,DYNIV-11,FLJ41912,HDYNIV,VPS1
    Gene ID
    10059
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