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C1QB antibody (C-Term)

C1QB Reactivity: Human, Dog, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2773842
  • Target See all C1QB Antibodies
    C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))
    Binding Specificity
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 47
    • 19
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Dog, Horse
    Host
    • 43
    • 5
    Rabbit
    Clonality
    • 45
    • 3
    Polyclonal
    Conjugate
    • 24
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This C1QB antibody is un-conjugated
    Application
    • 30
    • 17
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    AYNTFQVTTG GMVLKLEQGE NVFLQATDKN SLLGMEGANS IFSGFLLFPD
    Predicted Reactivity
    Dog: 92%, Horse: 82%, Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against C1QB. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human C1QB
    Top Product
    Discover our top product C1QB Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 253 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Takamori, Atsuta, Nakamura, Sawase, Koyano, Hara: "Histopathological comparison of the onset of peri-implantitis and periodontitis in rats." in: Clinical oral implants research, Vol. 28, Issue 2, pp. 163-170, (2016) (PubMed).

    Noguchi, Ukai, Kuramoto, Yoshinaga, Nakamura, Takamori, Yamashita, Hara: "The histopathological comparison on the destruction of the periodontal tissue between normal junctional epithelium and long junctional epithelium." in: Journal of periodontal research, Vol. 52, Issue 1, pp. 74-82, (2016) (PubMed).

    Nakatsu, Yoshinaga, Kuramoto, Nagano, Ichimura, Oshino, Yoshimura, Yano, Hara: "Occlusal trauma accelerates attachment loss at the onset of experimental periodontitis in rats." in: Journal of periodontal research, Vol. 49, Issue 3, pp. 314-22, (2014) (PubMed).

    Nagano, Kaneko, Yoshinaga, Ukai, Kuramoto, Nakatsu, Oshino, Ichimura, Hara: "Gram-positive bacteria as an antigen topically applied into gingival sulcus of immunized rat accelerates periodontal destruction." in: Journal of periodontal research, Vol. 48, Issue 4, pp. 420-7, (2013) (PubMed).

    Kuramoto, Yoshinaga, Kaneko, Ukai, Shiraishi, Oshino, Ichimura, Hara: "The formation of immune complexes is involved in the acute phase of periodontal destruction in rats." in: Journal of periodontal research, Vol. 47, Issue 4, pp. 455-62, (2012) (PubMed).

    Yoshinaga, Ukai, Kaneko, Nakatsu, Shiraishi, Kuramoto, Oshino, Ichimura, Hara: "Topical application of lipopolysaccharide into gingival sulcus promotes periodontal destruction in rats immunized with lipopolysaccharide." in: Journal of periodontal research, Vol. 47, Issue 5, pp. 674-80, (2012) (PubMed).

  • Target
    C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))
    Alternative Name
    C1QB (C1QB Products)
    Synonyms
    complement C1q B chain antibody, complement component 1, q subcomponent, beta polypeptide antibody, C1QB antibody, C1qb antibody
    Background
    C1QB is a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. C1QB is the B-chain polypeptide of human complement subcomponent C1q.This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q.
    Alias Symbols: -
    Protein Interaction Partner: IL32, EED, FN1, EDA2R, RELA, MYOC, PTX3, C1R, HRG, DEFA1, C1QC, C1QA,
    Protein Size: 253
    Molecular Weight
    27 kDa
    Gene ID
    713
    NCBI Accession
    NM_000491, NP_000482
    UniProt
    P02746
    Pathways
    Complement System
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