CYP3A4 antibody (Middle Region)
-
- Target See all CYP3A4 Antibodies
- CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
-
Binding Specificity
- Middle Region
-
Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep, Goat, Horse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This CYP3A4 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- MIPSYALHRD PKYWTEPEKF LPERFSKKNK DNIDPYIYTP FGSGPRNCIG
- Predicted Reactivity
- Cow: 86%, Dog: 85%, Goat: 86%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Sheep: 86%
- Characteristics
- This is a rabbit polyclonal antibody against CYP3A4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CYP3A4
- Top Product
- Discover our top product CYP3A4 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 503 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance." in: Clinical pharmacology and therapeutics, Vol. 95, Issue 4, pp. 416-22, (2014) (PubMed).
: "
-
Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance." in: Clinical pharmacology and therapeutics, Vol. 95, Issue 4, pp. 416-22, (2014) (PubMed).
-
- Target
- CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
- Alternative Name
- CYP3A4 (CYP3A4 Products)
- Synonyms
- CP33 antibody, CP34 antibody, CYP3A antibody, CYP3A3 antibody, CYPIIIA3 antibody, CYPIIIA4 antibody, HLP antibody, NF-25 antibody, P450C3 antibody, P450PCN1 antibody, MGC108372 antibody, CYP3A80 antibody, CYP3A4 antibody, CYP3A21 antibody, CYPIIIA21 antibody, CYP3A12 antibody, cytochrome P450 family 3 subfamily A member 4 antibody, cytochrome P450 family 3 subfamily A member 43 antibody, cytochrome P450 3A4 antibody, cytochrome P450, subfamily IIIA, polypeptide 4 antibody, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 antibody, cytochrome P450, family 3, subfamily A, polypeptide 4 antibody, CYP3A4 antibody, CYP3A43 antibody, PTRG_01782 antibody, PTRG_06060 antibody, cyp3a4 antibody
- Background
-
This gene, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This prot
Alias Symbols: CP33, CP34, CYP3A, CYP3A3, HLP, MGC126680, NF-25, P450C3, P450PCN1, CYPIIIA3, CYPIIIA4
Protein Interaction Partner: UBC, PRKCA, PRKACA, PGRMC1, POR, GK, CYB5A, STUB1, AMFR, UGT2B7,
Protein Size: 503 - Molecular Weight
- 57 kDa
- Gene ID
- 1576
- NCBI Accession
- NM_017460, NP_059488
- UniProt
- P08684
- Pathways
- Steroid Hormone Biosynthesis
-