Anti-MOG IgG ELISA Kit

Catalog No. ABIN1882533

Product Details

Target: Anti-MOG IgG

Reactivity: Mouse

Detection Method: Colorimetric

Method Type: Competition ELISA

Application: ELISA

Brand: SensoLyte®

Analytical Method: Quantitative

Characteristics: The SensoLyte® Anti-Mouse MOG (1-125) IgG Quantitative ELISA Kit provides a convenient quantitative assay for anti-mouse MOG (1-125) autoantibody. This colorimetric assay is useful to researchers for determining the amount of anti-mouse MOG (1-125) antibody present, and can help provide information on the role it plays in the development and treatment of EAE, an animal model for multiple sclerosis pathogenesis.

Application Details

Comment:

ELISA Kit

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C

Storage Comment: Store all kit components at 2-8 °C for up to 6 months.

Expiry Date: 6 months

References

Molnarfi, Schulze-Topphoff, Weber, Patarroyo, Prodhomme, Varrin-Doyer, Shetty, Linington, Slavin, Hidalgo, Jenne, Wekerle, Sobel, Bernard, Shlomchik, Zamvil: "MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies." in: The Journal of experimental medicine, Vol. 210, Issue 13, pp. 2921-37, (2013) (PubMed).

deLuca, Pikor, OLeary, Galicia-Rosas, Ward, Defreitas, Finlay, Ousman, Osborne, Gommerman: "Substrain differences reveal novel disease-modifying gene candidates that alter the clinical course of a rodent model of multiple sclerosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 6, pp. 3174-85, (2010) (PubMed).

Target Details

Target: Anti-MOG IgG

Target Type: Antibody

Background: Mouse MOG recombinant protein (1-125) is able to induces autoantibody production and relapsing-remitting neurological disease causing extensive plaque-like demyelination. Autoantibody response to mouse MOG (1-125) has been observed in induced experimental autoimmune encephalomyelitis (EAE) in C57/BL6, 129/Sv, B6, and SJL mice.