NF-kB p65 antibody (C-Term)

Catalog No. ABIN4889656

Product Details anti-NF-kB p65 Antibody

Target: NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NF-kB p65 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Purification: None

Immunogen: This NFkB p65 antibody was raised against a peptide immunogen corresponding to the C-terminal of human p65.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-NF-kB p65 antibody (ABIN4889656)

Diermeier, Kolovos, Heizinger, Schwartz, Georgomanolis, Zirkel, Wedemann, Grosveld, Knoch, Merkl, Cook, Längst, Papantonis: "TNF? signalling primes chromatin for NF-?B binding and induces rapid and widespread nucleosome repositioning." in: Genome biology, Vol. 15, Issue 12, pp. 536, (2015) (PubMed).

Raaz, Schellinger, Chernogubova, Warnecke, Kayama, Penov, Hennigs, Salomons, Eken, Emrich, Zheng, Adam, Jagger, Nakagami, Toh, Toyama, Deng, Buerke, Maegdefessel, Hasenfuß, Spin, Tsao: "Transcription Factor Runx2 Promotes Aortic Fibrosis and Stiffness in Type 2 Diabetes Mellitus." in: Circulation research, Vol. 117, Issue 6, pp. 513-24, (2015) (PubMed).

Anderson, Rahmutula, Gardner: "Tumor necrosis factor-alpha inhibits endothelial nitric-oxide synthase gene promoter activity in bovine aortic endothelial cells." in: The Journal of biological chemistry, Vol. 279, Issue 2, pp. 963-9, (2004) (PubMed).

Target Details for NF-kB p65

Target: NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))

Alternative Name: NFkappaB p65 (NFkBP65 Products)

Synonyms: C-Rel antibody, NFKB3 antibody, p65 antibody, NFkB antibody, c-rel antibody, zgc:100833 antibody, Xrel2 antibody, Xrel3 antibody, rel antibody, rel-A antibody, rel2 antibody, rel3 antibody, v-rel antibody, xrel antibody, REL proto-oncogene, NF-kB subunit antibody, RELA proto-oncogene, NF-kB subunit antibody, v-rel reticuloendotheliosis viral oncogene homolog A (avian) antibody, v-rel avian reticuloendotheliosis viral oncogene homolog antibody, v-rel avian reticuloendotheliosis viral oncogene homolog L homeolog antibody, REL antibody, RELA antibody, Rela antibody, Rel antibody, rel antibody, rel.L antibody

Molecular Weight: 65 kDa

Gene ID: 5970

Pathways: NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins