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SLC11A2 antibody (AA 1-65)

SLC11A2 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 4C6 unconjugated
Catalog No. ABIN562043
  • Target See all SLC11A2 Antibodies
    SLC11A2 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2))
    Binding Specificity
    • 16
    • 15
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    AA 1-65
    Reactivity
    • 42
    • 34
    • 21
    • 16
    • 15
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 63
    • 2
    Mouse
    Clonality
    • 64
    • 2
    Monoclonal
    Conjugate
    • 23
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SLC11A2 antibody is un-conjugated
    Application
    • 40
    • 30
    • 26
    • 26
    • 15
    • 14
    • 10
    • 9
    • 6
    • 6
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant SLC11A2.
    Sequence
    MVLGPEQKMS DDSVSGDHGE SASLGNINPA YSNPSLSQSP GDSEEYFATY FNEKISIPEE EYSCF
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    SLC11A2 (NP_000608, 1 a.a. ~ 65 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    4C6
    Isotype
    IgG2a
    Top Product
    Discover our top product SLC11A2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Montalbetti, Simonin, Simonin, Awale, Reymond, Hediger: "Discovery and characterization of a novel non-competitive inhibitor of the divalent metal transporter DMT1/SLC11A2." in: Biochemical pharmacology, Vol. 96, Issue 3, pp. 216-24, (2015) (PubMed).

    Montalbetti, Simonin, Dalghi, Kovacs, Hediger: "Development and Validation of a Fast and Homogeneous Cell-Based Fluorescence Screening Assay for Divalent Metal Transporter 1 (DMT1/SLC11A2) Using the FLIPR Tetra." in: Journal of biomolecular screening, Vol. 19, Issue 6, pp. 900-908, (2014) (PubMed).

    Howitt, Putz, Lackovic, Doan, Dorstyn, Cheng, Yang, Chan-Ling, Silke, Kumar, Tan: "Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 36, pp. 15489-94, (2009) (PubMed).

    Foot, Dalton, Shearwin-Whyatt, Dorstyn, Tan, Yang, Kumar: "Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2." in: Blood, Vol. 112, Issue 10, pp. 4268-75, (2008) (PubMed).

  • Target
    SLC11A2 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2))
    Alternative Name
    SLC11A2 (SLC11A2 Products)
    Synonyms
    DCT1 antibody, DMT1 antibody, NRAMP2 antibody, Nramp2 antibody, mk antibody, van antibody, Dmt1 antibody, ATNRAMP2 antibody, F8G22.4 antibody, F8G22_4 antibody, NRAMP metal ion transporter 2 antibody, dct1 antibody, dmt1 antibody, nramp2 antibody, SLC11A2 antibody, cb426 antibody, fa07b10 antibody, wu:fa07b10 antibody, zgc:136699 antibody, solute carrier family 11 member 2 antibody, solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 antibody, NRAMP metal ion transporter 2 antibody, manganese transport protein antibody, metal transporter Nramp2 antibody, solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 antibody, SLC11A2 antibody, Slc11a2 antibody, NRAMP2 antibody, LOC9327403 antibody, slc11a2 antibody
    Background
    Full Gene Name: solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
    Synonyms: DCT1,DMT1,FLJ37416,NRAMP2
    Gene ID
    4891
    NCBI Accession
    NM_000617
    Pathways
    Transition Metal Ion Homeostasis, Proton Transport, Positive Regulation of Endopeptidase Activity
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