SOX10 antibody (AA 191-240)

Catalog No. ABIN6746058

Product Details anti-SOX10 Antibody

Target: SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))

Binding Specificity: AA 191-240

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Human SOX10

Predicted Reactivity: Percent identity by BLAST analysis: Human (100%) Mouse, Dog, Bovine, Rabbit, Horse, Pig, Guinea pig (92%) Rat (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa191-240 of human SOX10 (P56693, NP_008872). Percent identity by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey (100%), Galago, Marmoset, Mouse, Hamster, Dog, Bovine, Bat, Rabbit, Horse, Pig, Guinea pig (92%), Rat, Elephant (85%), Opossum, Zebra finch (84%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P, WB (0.25 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-SOX10 antibody (ABIN6746058)

Suhr, Senut, Whitelegge, Faull, Cuizon, Gage: "Identities of sequestered proteins in aggregates from cells with induced polyglutamine expression." in: The Journal of cell biology, Vol. 153, Issue 2, pp. 283-94, (2001) (PubMed).

Hunt, Morimoto: "Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 82, Issue 19, pp. 6455-9, (1985) (PubMed).

Target Details for SOX10

Target: SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))

Alternative Name: SOX10 (SOX10 Products)

Synonyms: DOM antibody, PCWH antibody, WS2E antibody, WS4 antibody, WS4C antibody, SOX-10 antibody, SOX10 antibody, dom antibody, ws4 antibody, Dom antibody, Sox21 antibody, SOX9 antibody, cls/sox10 antibody, zgc:100757 antibody, SRY-box 10 antibody, SRY box 10 antibody, SRY-box 10 L homeolog antibody, SRY (sex determining region Y)-box 10 antibody, SOX10 antibody, Sox10 antibody, sox10.L antibody, sox10 antibody

Background: Name/Gene ID: SOX10
Family: Transcription factor

Synonyms: SOX10, DOM, Transcription factor SOX-10, WS4, PCWH, WS2E, SRY-related HMG-box gene 10, WS4C

Gene ID: 6663

NCBI Accession: NP_008872

UniProt: P56693

Pathways: Chromatin Binding