CHAF1A antibody

Catalog No. ABIN2668347

Product Details anti-CHAF1A Antibody

Target: CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))

Reactivity: Human

Host: Hamster

Clonality: Monoclonal

Conjugate: This CHAF1A antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)

Purification: Protein G Chromatography

Immunogen: The CAF-1 p150 antobody was raised against full-length CAF-1 purified from human 293 cells.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-CHAF1A antibody (ABIN2668347)

Hoek, Stillman: "Chromatin assembly factor 1 is essential and couples chromatin assembly to DNA replication in vivo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 21, pp. 12183-8, (2003) (PubMed).

Kaufman, Kobayashi, Kessler, Stillman: "The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication." in: Cell, Vol. 81, Issue 7, pp. 1105-14, (1995) (PubMed).

Smith, Stillman: "Immunological characterization of chromatin assembly factor I, a human cell factor required for chromatin assembly during DNA replication in vitro." in: The Journal of biological chemistry, Vol. 266, Issue 18, pp. 12041-7, (1991) (PubMed).

Target Details for CHAF1A

Target: CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))

Alternative Name: CAF-1 p150 (CHAF1A Products)

Synonyms: CHAF1A antibody, CAF-1 antibody, CAF1 antibody, CAF1B antibody, CAF1P150 antibody, P150 antibody, AL023013 antibody, AL024058 antibody, Cac1p antibody, CAF-1P150 antibody, CAF-I-p150 antibody, CAF-Ip150 antibody, caip150 antibody, wu:fd14g10 antibody, zgc:153930 antibody, chaf1a-b antibody, xp150 antibody, chromatin assembly factor 1 subunit A antibody, chromatin assembly factor 1, subunit A (p150) antibody, chromatin assembly factor 1 subunit A S homeolog antibody, Chaf1a antibody, CHAF1A antibody, LOC100447657 antibody, chaf1a antibody, chaf1a.S antibody

Background: CAF-1 p150 (Chromatin assembly factor-1 p150 subunit, CAF1A, CHAF1A) is the largest subunit of the CAF-1 complex that is required for the assembly of nucleosomes onto newly replicated DNA. Specifically, CAF-1 assists in the loading of the H3-H4 tetramer and may be involved in DNA damage repair.

Molecular Weight: 150 kDa

Gene ID: 10036