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DNAJB1 antibody

DNAJB1 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB1770 unconjugated
Catalog No. ABIN1882092
  • Target See all DNAJB1 Antibodies
    DNAJB1 (DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1))
    Reactivity
    • 72
    • 35
    • 31
    • 12
    • 11
    • 10
    • 8
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 71
    • 35
    Rabbit
    Clonality
    • 71
    • 35
    Polyclonal
    Conjugate
    • 47
    • 9
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DNAJB1 antibody is un-conjugated
    Application
    • 91
    • 41
    • 40
    • 39
    • 39
    • 28
    • 11
    • 9
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This HSP40 antibody is generated from rabbits immunized with a recombinant protein encoding full length of human HSP40.
    Clone
    RB1770
    Isotype
    Ig Fraction
    Top Product
    Discover our top product DNAJB1 Primary Antibody
  • Application Notes
    WB: 1:4000. IHC-P: 1:50~100. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Ohtsuka, Hata: "Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature." in: Cell stress & chaperones, Vol. 5, Issue 2, pp. 98-112, (2001) (PubMed).

    Hata, Ohtsuka: "Characterization of HSE sequences in human Hsp40 gene: structural and promoter analysis." in: Biochimica et biophysica acta, Vol. 1397, Issue 1, pp. 43-55, (1998) (PubMed).

    Hata, Okumura, Seto, Ohtsuka: "Genomic cloning of a human heat shock protein 40 (Hsp40) gene (HSPF1) and its chromosomal localization to 19p13.2." in: Genomics, Vol. 38, Issue 3, pp. 446-9, (1997) (PubMed).

  • Target
    DNAJB1 (DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1))
    Alternative Name
    HSP40 (DNAJB1 Products)
    Synonyms
    HSPF1 antibody, Hdj1 antibody, Hsp40 antibody, RSPH16B antibody, Sis1 antibody, CG10578 antibody, DNAJ-1 antibody, DNAJ1 antibody, DROJ1 antibody, Dmel\\CG10578 antibody, DnaJ1 64EF antibody, DroJ1 antibody, EU3500 antibody, HSP40 antibody, HSP40/HDJ1 antibody, Hsp-40 antibody, anon-WO0140519.166 antibody, anon-WO0172774.135 antibody, dHDJ1 antibody, dHDJ1/HSP40 antibody, dHdj1 antibody, dhdJ1 antibody, dhdj-1 antibody, dhdj1 antibody, dnaJ-1 antibody, droj1 antibody, hsp40 antibody, dnajb4 antibody, hdj1 antibody, hspf1 antibody, sis1 antibody, DnaJ-5 antibody, MAS5 antibody, dnaJ antibody, 0610007I11Rik antibody, dnajb1 antibody, zf-Hsp40 antibody, zgc:101068 antibody, DnaJ heat shock protein family (Hsp40) member B1 antibody, DnaJ-like-1 antibody, DnaJ (Hsp40) homolog 5 antibody, type I HSP40 co-chaperone YDJ1 antibody, DnaJ protein antibody, molecular chaperone DnaJ antibody, DnaJ (Hsp40) homolog, subfamily B, member 1a antibody, DNAJB1 antibody, Dnajb1 antibody, DnaJ-1 antibody, dnajb1 antibody, DnaJ-5 antibody, YDJ1 antibody, dnaJ antibody, dnajb1a antibody
    Background
    DnaJ (Hsp40) belongs to the DnaJ-class of molecular chaperones with a C-terminal Zn finger domain. HSP40 (DnaJ) together with DnaK and GrpE form a molecular chaperone that is involved in formation of protein complexes, protein folding, prevention of protein aggregation, and protein turnover and export. Several human neurodegenerative diseases involve the expansion of a polyglutamine within the disease proteins. Molecular chaperones such as HSP40 complexes can modulate polyglutamine pathogenesis In transgenic Drosophila disease models of Machado-Joseph disease and Huntington disease Hdj1, the Drosophila homolog to human HSP40, demonstrates substrate specificity for polyglutamine proteins suppression in combination with other molecular chapterones of neurotoxicity, and altered solubility of mutant polyglutamine proteins.
    Molecular Weight
    38044
    NCBI Accession
    NP_006136
    UniProt
    P25685
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